急性肾损伤：从诊断到预防及治疗策略
Acute Kidney Injury: From Diagnosis to Prevention and Treatment Strategies.
作者信息
Gameiro Joana, Fonseca José Agapito, Outerelo Cristina, Lopes José António
机构信息
Department of Medicine, Division of Nephrology and Renal Transplantation, Centro Hospitalar Lisboa Norte, EPE, Av. Prof. Egas Moniz, 1649-035 Lisboa, Portugal.
出版信息
J Clin Med. 2020 Jun 2;9(6):1704. doi: 10.3390/jcm9061704.
Abstract
Acute kidney injury (AKI) is characterized by an acute decrease in renal function that can be multifactorial in its origin and is associated with complex pathophysiological mechanisms. In the short term, AKI is associated with an increased length of hospital stay, health care costs, and in-hospital mortality, and its impact extends into the long term, with AKI being associated with increased risks of cardiovascular events, progression to chronic kidney disease (CKD), and long-term mortality. Given the impact of the prognosis of AKI, it is important to recognize at-risk patients and improve preventive, diagnostic, and therapy strategies. The authors provide a comprehensive review on available diagnostic, preventive, and treatment strategies for AKI.
摘要
急性肾损伤（AKI）的特征是肾功能急性下降，其病因可能是多因素的，并且与复杂的病理生理机制相关。短期内，AKI与住院时间延长、医疗费用增加以及住院死亡率升高有关，其影响会延伸至长期，AKI与心血管事件风险增加、进展为慢性肾脏病（CKD）以及长期死亡率升高有关。鉴于AKI预后的影响，识别高危患者并改进预防、诊断和治疗策略很重要。作者对现有的AKI诊断、预防和治疗策略进行了全面综述。
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