Faculty of Medicine, University of Ljubljana, Zaloška 9, 1000, Ljubljana, Slovenia.
Department of Orthopaedic Surgery, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Arch Orthop Trauma Surg. 2020 Sep;140(9):1275-1283. doi: 10.1007/s00402-020-03517-0. Epub 2020 Jun 9.
The third-generation Zweymüller hip endoprosthesis has been used for decades with excellent results in arthroplasty registries, but surgeon-stratified reports on this implant are still scarce. The aim of the presented single-hospital cohort analysis of the third-generation Endoplus-Zweymüller primary total hip arthroplasty was to determine implant survival rates until the first revision/removal at 10/15/20/25 years after implantation and to find out whether implant survival depended on the operating surgeon, patient's age and gender, operated side (right/left), season of the year and the set of implanted components (SL-PLUS femur, BICON-PLUS acetabulum or both components).
The retrospective observational cohort study included 1976 consecutive patients with primary BICON/SL-PLUS Zweymüller hip endoprosthesis implanted at the same operating theater block of the University Medical Centre Ljubljana, Department of Orthopaedic Surgery (Ljubljana, Slovenia) between January 1, 1993 and May 1, 2014. Survival analyses were performed with the Kaplan-Meier method and the Cox regression analysis after minimum 5 and maximum 26 years of follow-up.
At 10/15/20/25 years after implantation, the cumulative proportion of revision-free surviving Zweymüller total hip endoprostheses was 92/90/85/81% and the cumulative proportion with unremoved immobile components was 93/91/87/84%, respectively. After adjustment for age, gender and operated side, less experienced surgeons (odds ratios 2.34-5.00), season of the year at primary implantation (spring vs. winter odds ratio 1.74) and the use of BICON-PLUS acetabulum with femoral stem from another manufacturer (odds ratio 2.23) were significant risk factors of worse implant survival.
The study presents the largest published third-generation Zweymüller BICON/SL-PLUS total hip arthroplasty cohort from a single non-developmental hospital with 23,255 component years of observation. Study findings indicate the impact of environmental factors at primary implantation and variability between different surgeons on the long-term implant survival.
第三代 Zweymüller 髋关节假体在关节置换登记处已经使用了几十年,效果非常好,但关于这种植入物的外科医生分层报告仍然很少。本研究对第三代 Endoplus-Zweymüller 初次全髋关节置换术进行了单中心队列分析,旨在确定植入后 10/15/20/25 年的首次翻修/取出率,并确定植入物的存活率是否取决于手术医生、患者的年龄和性别、手术侧(右侧/左侧)、一年中的季节以及植入组件集(SL-PLUS 股骨、BICON-PLUS 髋臼或两者组件)。
本回顾性观察性队列研究纳入了 1976 例连续患者,他们在 1993 年 1 月 1 日至 2014 年 5 月 1 日期间在卢布尔雅那大学医学中心骨科手术部(卢布尔雅那,斯洛文尼亚)同一手术室接受了原发性 BICON/SL-PLUS Zweymüller 髋关节假体植入。采用 Kaplan-Meier 法和 Cox 回归分析进行生存分析,随访时间最短为 5 年,最长为 26 年。
植入后 10/15/20/25 年,无翻修存活的 Zweymüller 全髋关节假体的累积比例分别为 92/90/85/81%,无移动固定组件的累积比例分别为 93/91/87/84%。调整年龄、性别和手术侧后,经验较少的外科医生(优势比 2.34-5.00)、初次植入时的季节(春季与冬季的优势比 1.74)以及使用来自另一家制造商的 BICON-PLUS 髋臼和股骨柄(优势比 2.23)是影响植入物存活率的显著危险因素。
本研究是来自单一一所非开发性医院的第三代 Zweymüller BICON/SL-PLUS 全髋关节置换术最大的已发表队列研究,观察了 23255 个组件年。研究结果表明,初次植入时环境因素和不同外科医生之间的差异对长期植入物存活率有影响。