Suppr超能文献

儿童新型冠状病毒肺炎的系列计算机断层扫描结果及特定临床特征:一例报告

Serial computed tomographic findings and specific clinical features of pediatric COVID-19 pneumonia: A case report.

作者信息

Chen Xing, Zou Xiao-Jie, Xu Zhen

机构信息

Department of Pediatrics, Huzhou Central Hospital, Affiliated Cent Hospital HuZhou University, Huzhou 313000, Zhejiang Province, China.

出版信息

World J Clin Cases. 2020 Jun 6;8(11):2345-2349. doi: 10.12998/wjcc.v8.i11.2345.

Abstract

BACKGROUND

A series of recent cases of pneumonia in Wuhan, Hubei Province, China, was caused by the 2019 novel coronavirus [2019-nCoV, also called severe acute respiratory syndrome (SARS)-CoV-2]. The World Health Organization officially named the disease as coronavirus disease 2019 (COVID-19). With the global spread of COVID-19, similar cases have appeared in other areas of China, and there are a few reports of pediatric patients with COVID-19 pneumonia.

CASE SUMMARY

A 7-year-old girl was diagnosed with COVID-19 and presented with irregular fever, sore throat and diarrhea. Chest computed tomography revealed patchy consolidation and ground-glass opacities in multiple areas. The lesions were mainly distributed in the bronchial bundles or subpleural areas of both lungs, particularly in the right lower lobe. The patient also presented with diarrhea, mild kidney injury, and live coronavirus was found in her feces. She was given antiviral agents (lopinavir and ritonavir), and follow-up detection showed that these abnormalities were markedly decreased within 3 d.

CONCLUSION

The clinical symptoms and prognosis of COVID-19 in pediatric patients may be different from those in adult patients, and the fecal-oral transmission of SARS-CoV-2 should be considered.

摘要

背景

中国湖北省武汉市近期出现的一系列肺炎病例由2019新型冠状病毒(2019-nCoV,也称为严重急性呼吸综合征冠状病毒2,即SARS-CoV-2)引起。世界卫生组织将该疾病正式命名为2019冠状病毒病(COVID-19)。随着COVID-19在全球范围内传播,中国其他地区也出现了类似病例,并且有一些关于COVID-19肺炎儿科患者的报道。

病例摘要

一名7岁女孩被诊断为COVID-19,表现为不规则发热、咽痛和腹泻。胸部计算机断层扫描显示多个区域有斑片状实变和磨玻璃样混浊。病变主要分布在双肺的支气管束或胸膜下区域,尤其是右下叶。该患者还出现腹泻、轻度肾损伤,并且在其粪便中发现了活冠状病毒。给予其抗病毒药物(洛匹那韦和利托那韦),随访检测显示这些异常在3天内明显减轻。

结论

儿科患者COVID-19的临床症状和预后可能与成人患者不同,应考虑SARS-CoV-2的粪-口传播。

相似文献

3
Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2.新型冠状病毒 2019 年 SARS-CoV-2 患者的影像学和临床特征。
Eur J Nucl Med Mol Imaging. 2020 May;47(5):1275-1280. doi: 10.1007/s00259-020-04735-9. Epub 2020 Feb 28.
4
COVID-19 Presented With Deep Vein Thrombosis: An Unusual Presenting.新冠病毒病表现为深静脉血栓形成:一种不寻常的表现。
J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620931239. doi: 10.1177/2324709620931239.

本文引用的文献

3
Genetic diversity and evolution of SARS-CoV-2.SARS-CoV-2 的遗传多样性与演化。
Infect Genet Evol. 2020 Jul;81:104260. doi: 10.1016/j.meegid.2020.104260. Epub 2020 Feb 21.
7
A novel coronavirus outbreak of global health concern.一场引发全球卫生关注的新型冠状病毒疫情。
Lancet. 2020 Feb 15;395(10223):470-473. doi: 10.1016/S0140-6736(20)30185-9. Epub 2020 Jan 24.
8
Medical Journals and the 2019-nCoV Outbreak.医学期刊与2019新型冠状病毒疫情
N Engl J Med. 2020 Feb 27;382(9):866. doi: 10.1056/NEJMe2001329. Epub 2020 Jan 27.
9
A Novel Coronavirus from Patients with Pneumonia in China, 2019.2019 年中国肺炎患者中的一种新型冠状病毒。
N Engl J Med. 2020 Feb 20;382(8):727-733. doi: 10.1056/NEJMoa2001017. Epub 2020 Jan 24.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验