Center for Research on Reproduction and Women's Health, Perelman School of Medicine University of Pennsylvania, Philadelphia, Pennsylvania.
Center of Excellence in Environmental Toxicology, Perelman School of Medicine University of Pennsylvania, Philadelphia, Pennsylvania.
Am J Physiol Endocrinol Metab. 2020 Aug 1;319(2):E315-E319. doi: 10.1152/ajpendo.00287.2020. Epub 2020 Jun 23.
The risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to maternal and newborn health has yet to be determined. Several reports suggest pregnancy does not typically increase the severity of maternal disease; however, cases of preeclampsia and preterm birth have been infrequently reported. Reports of placental infection and vertical transmission are rare. Interestingly, despite lack of SARS-CoV-2 placenta infection, there are several reports of significant abnormalities in placenta morphology. Continued research on pregnant women infected with SARS-CoV-2 and their offspring is vitally important.
严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)对孕产妇和新生儿健康的风险尚未确定。有几项报告表明,妊娠通常不会增加母体疾病的严重程度;然而,子痫前期和早产的病例时有报道。胎盘感染和垂直传播的报道很少见。有趣的是,尽管没有 SARS-CoV-2 胎盘感染的报告,但有几例报道称胎盘形态存在明显异常。对感染 SARS-CoV-2 的孕妇及其后代的持续研究至关重要。