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伴有右臂失用症的非惊厥性癫痫持续状态:一例报告

Non-convulsive status epilepticus with right arm apraxia: A case report.

作者信息

Ladisich Barbara, Otto Ferdinand, Machegger Lukas, Kleindienst Waltraud, Trinka Eugen, Kuchukhidze Giorgi

机构信息

Department of Neurology, Christian Doppler Klinik, University Hospital Paracelsus Medical University, Salzburg, Austria.

Department of Neurosurgery, Christian Doppler Klinik, University Hospital Paracelsus Medical University, Salzburg, Austria.

出版信息

Epilepsy Behav Rep. 2020 Jun 2;14:100371. doi: 10.1016/j.ebr.2020.100371. eCollection 2020.

Abstract

Non-convulsive SE (NCSE) is characterized by altered consciousness with or without slight motor manifestations or other phenomena such as aphasia, sensory, auditory, emotional, gustatory or other symptoms. A 69-year-old right-handed man developed the sudden onset of apraxia in his right arm. On admission, the patient was alert and well oriented. In his past medical history, an intracerebral hematoma (ICH) in the left temporo-parietal area was noted occurred five years before the current admission. An electroencephalography (EEG) showed rhythmic theta-delta activity with fluctuating frequency between 1.5 and 5 Hz in the left centro-parieto-temporal area, which promptly responded to the intravenous injection of 2 mg clonazepam and 1000 mg levetiracetam. Apraxia resolved completely and the EEG demonstrated intermittent non-rhythmic delta-theta slowing in the left temporo-parietal area. A cranial CT scan showed residual cystic encephalomalacia in the left temporo-parietal area due to the previous ICH. An MRI exhibited an old parenchymal defect in the left temporo-parietal area with a residual hemosiderin rim on the susceptibility weighted imaging (SWI) and no diffusion restriction on the diffusion weighted image (DWI). NCSE presented with right arm apraxia in our patient with a post-hemorrhagic residual parenchymal defect in the left temporo-parietal area.

摘要

非惊厥性癫痫持续状态(NCSE)的特征是意识改变,伴有或不伴有轻微运动表现或其他现象,如失语、感觉、听觉、情感、味觉或其他症状。一名69岁右利手男性突然出现右臂失用症。入院时,患者意识清醒,定向力良好。既往病史显示,在本次入院前五年,左侧颞顶叶区域曾发生过脑内血肿(ICH)。脑电图(EEG)显示左侧中央顶颞区有节律性θ-δ活动,频率在1.5至5Hz之间波动,静脉注射2mg氯硝西泮和1000mg左乙拉西坦后迅速出现反应。失用症完全缓解,脑电图显示左侧颞顶叶区域间歇性无节律性δ-θ减慢。头颅CT扫描显示,由于既往ICH,左侧颞顶叶区域存在残留的囊性脑软化。MRI显示左侧颞顶叶区域有陈旧性实质缺损,在磁敏感加权成像(SWI)上有残留的含铁血黄素边缘,在弥散加权成像(DWI)上无弥散受限。在我们的患者中,NCSE表现为右臂失用症,左侧颞顶叶区域有出血后残留的实质缺损。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12d1/7303554/fb68d0784f77/gr1.jpg

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