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新型冠状病毒肺炎与皮肤病学。

COVID-19 and dermatology.

机构信息

Department of Dermatology, Gülhane Faculty of Medicine, Health Sciences University, İstanbul, Turkey

出版信息

Turk J Med Sci. 2020 Dec 17;50(8):1751-1759. doi: 10.3906/sag-2005-182.

Abstract

BACKGROUND/AIM: Sars-CoV-2 virus infection (COVID-19) was observed in China in the last months of 2019. In the period following, this infection spread all over the world. In March 2020 the World Health Organization announced the existence of a pandemic. The aim of this manuscript is to investigate skin diseases associated with COVID-19 under three main headings: skin problems related to personal protective equipment and personal hygiene measures, skin findings observed in SARS-CoV-2 virus infections, and skin findings due to COVID-19 treatment agents.

MATERIALS AND METHODS

In PubMed, Google Scholar databases, skin lesions related to personal protective equipment and personal hygiene measures, skin findings observed in SARS-CoV-2 virus infections and skin findings due to COVID-19 treatment agents subjects are searched in detail.

RESULTS

Pressure injury, contact dermatitis, itching, pressure urticaria, exacerbation of preexisting skin diseases, and new skin lesion occurrence/new skin disease occurrence may be due to personal protective equipment. Skin problems related to personal hygiene measures could include itching, dryness, and contact dermatitis. Skin findings may also be observed in SARS-CoV-2 virus infections. The incidence of skin lesions due to COVID-19 was reported to be between 0.2% and 29%. Many skin lesions including maculopapular, urticarial, vesicular, chilblain-like, thrombotic/ischemic, etc. are observed in COVID-19 patients. Some authors have stated that there is an absence of SARS-CoV-2 virus infection-specific skin findings. However, in asymptomatic or presymptomatic COVID-19 patients in particular, skin lesions can lead to the diagnosis of COVID-19. In addition, skin lesions may occur due to COVID-19 treatment agents.

CONCLUSION

Many skin lesions may appear as a result of COVID-19. Even in the absence of a COVID-19 diagnosis, skin findings should be evaluated carefully in this pandemic period.

摘要

背景/目的:Sars-CoV-2 病毒感染(COVID-19)于 2019 年末在中国被发现。此后,该感染在全球范围内传播。2020 年 3 月,世界卫生组织宣布存在大流行。本文旨在从三个主要方面探讨与 COVID-19 相关的皮肤病:与个人防护设备和个人卫生措施相关的皮肤问题、SARS-CoV-2 病毒感染中观察到的皮肤表现,以及 COVID-19 治疗药物引起的皮肤表现。

材料和方法

在 PubMed、Google Scholar 数据库中,详细检索与个人防护设备和个人卫生措施相关的皮肤损伤、SARS-CoV-2 病毒感染相关的皮肤表现以及 COVID-19 治疗药物引起的皮肤表现的主题。

结果

压力性损伤、接触性皮炎、瘙痒、压力性荨麻疹、原有皮肤病加重以及新的皮肤病变/新发皮肤病可能与个人防护设备有关。与个人卫生措施相关的皮肤问题可能包括瘙痒、干燥和接触性皮炎。SARS-CoV-2 病毒感染也可能出现皮肤表现。COVID-19 患者的皮肤病变发生率报告在 0.2%至 29%之间。许多皮肤病变,包括斑丘疹、荨麻疹、水疱、冻疮样、血栓/缺血性等,在 COVID-19 患者中观察到。一些作者指出,没有 SARS-CoV-2 病毒感染特异性的皮肤表现。然而,特别是在无症状或出现症状前的 COVID-19 患者中,皮肤病变可能导致 COVID-19 的诊断。此外,COVID-19 治疗药物也可能引起皮肤病变。

结论

许多皮肤病变可能是 COVID-19 的结果。即使没有 COVID-19 的诊断,在大流行期间也应仔细评估皮肤表现。

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