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使用哮喘药物依从性报告量表评估科威特成年哮喘患者吸入性糖皮质激素的依从性。

Assessing Adherence to Inhaled Corticosteroids Among Adults with Asthma in Kuwait Using the Medication Adherence Report Scale for Asthma.

作者信息

Albassam Abdullah, Alharbi Amal, Awaisu Ahmed

机构信息

Department of Pharmacy Practice, Faculty of Pharmacy, Kuwait University, Kuwait City, Kuwait.

Department of Pharmacy, Farwaniya Hospital, Ministry of Health, Kuwait City, Kuwait.

出版信息

Patient Prefer Adherence. 2020 Jun 9;14:963-970. doi: 10.2147/PPA.S248655. eCollection 2020.

Abstract

PURPOSE

Inhaled corticosteroids (ICS) are the mainstay maintenance therapy for asthma management. Non-adherence to ICS, which can lead to exacerbations and poor asthma control, is commonly reported among adult patients with asthma. The level of adherence to ICS among adult patients with asthma in Kuwait has not been previously published. The aim of this study was to assess adherence to ICS among adults with asthma in Kuwait.

PATIENTS AND METHODS

A cross-sectional study was conducted among adult patients with asthma using ICS therapy at ambulatory asthma clinics in Kuwait. Adherence to ICS was assessed using the Medication Adherence Report Scale for Asthma (MARS-A). Descriptive and logistic regression analyses were conducted using SPSS version 23.

RESULTS

One hundred and forty-nine patients with a mean age of 41.42 (12.75) years participated in the study. The majority of the participants (82.6%) reported low adherence to ICS. Approximately, three-quarters of the participants reported that they used ICS either when needed or when they felt breathless. Furthermore, about half of them admitted that they tried to avoid using ICS (46.3%), or forgot to take ICS (51%), or only used ICS before performing an exercise that made them breathless (54%). In the multivariate logistic regression analysis, independent predictors (age, education, and smoking status) were not found to significantly influence the overall adherence to ICS therapy.

CONCLUSION

Adherence to ICS among adult patients with asthma was found to be low in ambulatory care settings in Kuwait. Future studies should aim to determine the barriers to ICS adherence among patients with asthma, with a focus on developing effective intervention strategies.

摘要

目的

吸入性糖皮质激素(ICS)是哮喘管理的主要维持治疗药物。在成年哮喘患者中,不坚持使用ICS的情况屡见不鲜,这可能导致病情加重和哮喘控制不佳。科威特成年哮喘患者对ICS的依从水平此前尚未发表。本研究的目的是评估科威特成年哮喘患者对ICS的依从性。

患者与方法

在科威特门诊哮喘诊所对使用ICS治疗的成年哮喘患者进行了一项横断面研究。使用哮喘药物依从性报告量表(MARS-A)评估对ICS的依从性。使用SPSS 23版进行描述性和逻辑回归分析。

结果

149名平均年龄为41.42(12.75)岁的患者参与了研究。大多数参与者(82.6%)报告对ICS的依从性较低。大约四分之三的参与者报告说,他们在需要时或感到呼吸困难时使用ICS。此外,约一半的人承认他们试图避免使用ICS(46.3%),或忘记服用ICS(51%),或仅在进行使他们呼吸困难的运动前使用ICS(54%)。在多变量逻辑回归分析中,未发现独立预测因素(年龄、教育程度和吸烟状况)对ICS治疗的总体依从性有显著影响。

结论

在科威特的门诊护理环境中,成年哮喘患者对ICS的依从性较低。未来的研究应旨在确定哮喘患者依从ICS的障碍,重点是制定有效的干预策略。

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