Ju Yeon Uk, Min Byung Wook
Division of Colon and Rectal Surgery, Department of Surgery, Korea University Guro Hospital, Seoul, Korea.
Ann Coloproctol. 2021 Apr;37(2):75-84. doi: 10.3393/ac.2020.04.01. Epub 2020 May 15.
Infectious complications are the biggest problem during bowel surgery, and one of the approaches to minimize them is the bowel cleaning method. It was expected that bowel cleaning could facilitate bowel manipulation as well as prevent infectious complications and further reduce anastomotic leakage. In the past, with the development of antibiotics, bowel cleaning and oral antibiotics (OA) were used together. However, with the success of emergency surgery and Enhanced Recovery After Surgery, bowel cleaning was not routinely performed. Consequently, bowel cleaning using OA was gradually no longer used. Recently, there have been reports that only bowel cleaning is not helpful in reducing infectious complications such as surgical site infection (SSI) compared to OA and bowel cleaning. Accordingly, in order to reduce SSI, guidelines are changing the trend of only intestinal cleaning. However, a consistent regimen has not yet been established, and there is still controversy depending on the location of the lesion and the surgical method. Moreover, complications such as Clostridium difficile infection have not been clearly analyzed. In the present review, we considered the overall bowel preparation trends and identified the areas that require further research.
感染性并发症是肠道手术期间最大的问题,而将其降至最低的方法之一是肠道清洁方法。人们期望肠道清洁既能便于肠道操作,又能预防感染性并发症,并进一步减少吻合口漏。过去,随着抗生素的发展,肠道清洁与口服抗生素(OA)一起使用。然而,随着急诊手术的成功和术后加速康复,肠道清洁不再常规进行。因此,使用OA进行肠道清洁逐渐不再被采用。最近,有报道称,与OA和肠道清洁相比,仅进行肠道清洁对减少手术部位感染(SSI)等感染性并发症并无帮助。因此,为了减少SSI,指南正在改变仅进行肠道清洁的趋势。然而,尚未建立一致的方案,并且根据病变部位和手术方法仍存在争议。此外,艰难梭菌感染等并发症尚未得到明确分析。在本综述中,我们考虑了整体肠道准备趋势,并确定了需要进一步研究的领域。