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经尿道膀胱肿瘤切除术质量和结果优化的最佳实践。

Best Practices to Optimise Quality and Outcomes of Transurethral Resection of Bladder Tumours.

机构信息

Stokes Centre for Urology, Royal Surrey Hospital, Guildford, UK.

Department of Urology, MD Anderson Cancer Center, Houston, TX, USA.

出版信息

Eur Urol Oncol. 2021 Feb;4(1):12-19. doi: 10.1016/j.euo.2020.06.010. Epub 2020 Jul 16.

Abstract

CONTEXT

Transurethral resection of bladder tumour (TURBT) for bladder cancer (BC) is an underappreciated common urological procedure. TURBT outcomes are highly variable, and results are dependent on judgement and surgical skill.

OBJECTIVE

To perform a narrative review and identify optimal best practice in TURBT including preparation, choice of equipment, procedural steps, surgical technique, and management of difficult scenarios and complications.

EVIDENCE ACQUISITION

Medline, Embase, and the Cochrane Central Register of Controlled Trials were searched. Important studies were identified and reviewed by an international panel of urologists representing major urological societies and guideline panels with a record of academic publication in this field. In areas where the group identified a lack of evidence or agreement, discussions took place until a consensus was reached.

EVIDENCE SYNTHESIS

A total of 814 studies were identified and 43 were included. The majority were retrospective (level of evidence 3), with only two prospective randomised trials. Four broad themes were identified, which formed the basis for the review: (1) the role of TURBT within the overall management of BC, (2) TURBT techniques, (3) measurement of outcomes including quality control and checklists, and (4) postoperative management. Familiarity with all aspects of the procedure is necessary to minimise morbidity and improve oncological outcomes. Development of new instruments and techniques, and prospective audit of TURBT outcomes are important future goals.

CONCLUSIONS

TURBT is a common and challenging operation with known variable outcomes. To reduce these variations and optimise outcomes, best practice based on evidence and expert opinion is recommended.

PATIENT SUMMARY

Transurethral resection of bladder tumour (TURBT) is a common but deceptively difficult urological operation. Optimal outcomes depend on experience and surgical skill. An international group of experienced TURBT surgeons review critical aspects of the procedure and share best practice to stimulate further discussion.

摘要

背景

经尿道膀胱肿瘤切除术(TURBT)是一种被低估的常见泌尿外科手术。TURBT 的结果差异很大,结果取决于判断和手术技巧。

目的

进行叙述性综述,并确定 TURBT 的最佳实践,包括准备、设备选择、手术步骤、手术技术以及处理困难情况和并发症。

证据获取

检索了 Medline、Embase 和 Cochrane 对照试验中心注册库。重要的研究由代表主要泌尿外科协会和指南小组的国际泌尿科医生小组确定并进行了审查,这些小组在该领域有学术出版物的记录。在小组确定缺乏证据或存在分歧的领域,进行了讨论,直到达成共识。

证据综合

共确定了 814 项研究,其中包括 43 项。大多数是回顾性研究(证据水平 3),只有两项前瞻性随机试验。确定了四个广泛的主题,这构成了综述的基础:(1)TURBT 在膀胱癌整体治疗中的作用,(2)TURBT 技术,(3)结果测量,包括质量控制和检查表,以及(4)术后管理。熟悉该程序的各个方面对于最大限度地减少发病率和提高肿瘤学结果是必要的。开发新的仪器和技术,以及前瞻性审核 TURBT 的结果是未来的重要目标。

结论

TURBT 是一种常见但具有挑战性的手术,其结果存在已知的差异。为了减少这些差异并优化结果,建议根据证据和专家意见制定最佳实践。

患者总结

经尿道膀胱肿瘤切除术(TURBT)是一种常见但颇具难度的泌尿外科手术。最佳结果取决于经验和手术技能。一组经验丰富的 TURBT 外科医生审查了该手术的关键方面,并分享了最佳实践,以激发进一步的讨论。

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