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在初级保健中使用胸部 X 光检查评估社区获得性肺炎 - 一项干预研究。

Use of chest X-ray in the assessment of community acquired pneumonia in primary care - an intervention study.

机构信息

Kärna Primary Healthcare Centre, Linköping, Sweden.

Kungsgatan Primary Healthcare Centre, Linköping, Sweden.

出版信息

Scand J Prim Health Care. 2020 Sep;38(3):323-329. doi: 10.1080/02813432.2020.1794404. Epub 2020 Jul 24.

Abstract

OBJECTIVES

The aim of this study was to explore if consequent use of chest X-ray (CXR), when the physician is not sure of the diagnosis of pneumonia after clinical examination and CRP-testing, favors a more restrictive prescribing of antibiotics.

DESIGN

This was an intervention study conducted between September 2015 and December 2017.

SETTING

Two intervention primary health care centers (PHCCs) and three control PHCCs in the southeast of Sweden.

INTERVENTION

All patients were referred for CXR when the physician´s suspicion of pneumonia was 'unsure', or 'quite sure' after CRP-testing. Control units managed patients according to their usual routine after clinical examination and CRP-testing.

SUBJECTS

A total of 104 patients were included in the intervention group and 81 patients in the control group. The inclusion criteria of the study were clinically suspected pneumonia in patients ≥18 years, with respiratory symptoms for more than 24 h. Antibiotic prescribing rate.

RESULTS

In the intervention group, 85% were referred for CXR and 69% were prescribed antibiotics, as compared to 26% and 77% in the control group. The difference in antibiotic prescribing rate was not statistically significant, unadjusted OR 0.68 [0.35-1.3] and adjusted OR 1.1 [CI 0.43-3.0]. A total of 24% of patients with negative CXR were prescribed antibiotics.

CONCLUSION

This study could not prove that use of CXR when the physician was not sure of the diagnosis of pneumonia results in lowered antibiotic prescribing rate in primary care. In cases of negative findings on CXR the physicians do not seem to rely on the outcome when it comes to antibiotic prescribing. Key Points Routine use of chest X-ray when the clinical diagnosis of pneumonia is uncertain has not been proven to result in lowered antibiotic prescribing rate. Physicians do not fully rely on chest X-ray outcome and to some extent prescribe antibiotics even if negative, when community-acquired pneumonia is suspected. Chest X-ray is already used in one out of four cases in routine primary care of pneumonia patients in Sweden.

摘要

目的

本研究旨在探讨临床检查和 C 反应蛋白(CRP)检测后,如果医生对肺炎的诊断不确定,是否会连续使用胸部 X 光(CXR),从而更严格地开具抗生素处方。

设计

这是一项在 2015 年 9 月至 2017 年 12 月期间进行的干预研究。

地点

瑞典东南部的两个干预初级保健中心(PHCC)和三个对照 PHCC。

干预措施

所有疑似肺炎的患者(CRP 检测后“不确定”或“相当确定”)均转诊行 CXR。对照单位根据临床检查和 CRP 检测后的常规程序管理患者。

研究对象

共纳入 104 例干预组患者和 81 例对照组患者。研究的纳入标准为年龄≥18 岁的患者有临床疑似肺炎,且有呼吸道症状超过 24 小时。抗生素处方率。

结果

干预组中,85%的患者转诊行 CXR,69%的患者开具抗生素,而对照组中分别为 26%和 77%。抗生素处方率的差异无统计学意义,未调整的 OR 0.68[0.35-1.3]和调整后的 OR 1.1[0.43-3.0]。24%的 CXR 阴性患者开具了抗生素。

结论

本研究无法证明临床诊断为肺炎但医生不确定时使用 CXR 会导致初级保健中抗生素处方率降低。在 CXR 结果为阴性的情况下,医生似乎不会在开具抗生素时完全依赖该结果。关键要点:当临床诊断为肺炎不确定时,常规使用胸部 X 光检查并不能证明会降低抗生素的处方率。当怀疑患有社区获得性肺炎时,医生并未完全依赖 CXR 结果,在某种程度上仍会开具抗生素,即使 CXR 结果为阴性。在瑞典,常规治疗肺炎患者时,已经有四分之一的患者使用了 CXR。

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