López-Valverde Nansi, Flores-Fraile Javier, López-Valverde Antonio
Department of Surgery, University of Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), 37007 Salamanca, Spain.
Biology (Basel). 2020 Jul 16;9(7):168. doi: 10.3390/biology9070168.
Although it was already described more than fifty years ago, there is yet no in-depth knowledge regarding the process of osseointegration as far as its mechanism of action is concerned. It could be one of the body's ways of reacting to a foreign body, where the individual's immune response capacity is involved. It is known that the nervous system has an impact on bone health and that the role of the autonomic nervous system in bone remodeling is an attractive field for current research. In the future, immuno/neuromodulatory techniques will open new and exciting lines of research.
尽管五十多年前就已对其有所描述，但就骨整合的作用机制而言，目前仍缺乏深入的了解。它可能是机体对外来物体的一种反应方式，其中涉及个体的免疫反应能力。众所周知，神经系统会对骨骼健康产生影响，并且自主神经系统在骨重塑中的作用是当前研究的一个引人关注的领域。未来，免疫/神经调节技术将开辟新的、令人兴奋的研究方向。
