University of Maryland School of Medicine, Baltimore, Maryland, USA.
Oxford University Clinical Research Unit, Patan Academy of Health Sciences, Kathmandu, Nepal.
Clin Infect Dis. 2020 Jul 29;71(Suppl 2):S155-S159. doi: 10.1093/cid/ciaa370.
Clinical trials of typhoid conjugate vaccine (TCV) are ongoing in 4 countries. Early data confirm safety, tolerability, and immunogenicity of typhoid conjugate vaccine, and early efficacy results are promising. These data support World Health Organization recommendations and planned country introductions. Forthcoming trial data will continue to inform programmatic use of typhoid conjugate vaccine.
伤寒结合疫苗（TCV）的临床试验正在 4 个国家进行。早期数据证实了伤寒结合疫苗的安全性、耐受性和免疫原性，早期疗效结果令人鼓舞。这些数据支持世界卫生组织的建议和计划中的国家引进。即将公布的试验数据将继续为伤寒结合疫苗的计划使用提供信息。
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