COVID-19 在大流行初期印度儿童中的流行病学和临床特征。
Epidemiological and Clinical Characteristics of COVID-19 in Indian Children in the Initial Phase of the Pandemic.
机构信息
Department of Pediatrics, Bharati Vidyapeeth Medical College and Hospital, Pune, Maharashtra, India.
Department of Pediatrics, Bharati Vidyapeeth Medical College and Hospital, Pune, Maharashtra, India. Correspondence to: Jitendra S Oswal, Professor, Department of Pediatrics, Bharati Vidyapeeth Medical College and Hospital, Pune 411043, Maharashtra, India.
出版信息
Indian Pediatr. 2020 Oct 15;57(10):914-917. doi: 10.1007/s13312-020-1994-4. Epub 2020 Jul 28.
OBJECTIVE
To assess the epidemiological and clinical characteristics of pediatric inpatients with COVID-19, early in the pandemic.
METHODS
Clinical and laboratory profile and outcomes were studied for children (aged 1 month - 18 years) presenting between 1 April, 2020 and 20 May, 2020 with positive nasopharyngeal swab for SARS-CoV-2 by RT-PCR.
RESULTS
50 children (56% male) with median (IQR) age of 6 (2-12) years were included. Majority (56%) were from families belonging to Kuppuswamy upper lower socioeconomic class. 45 (90%) had positive household contact, and 33 (66%) had overcrowding at home. 29 (58%) children were asymptomatic while 20 (40%) had mild symptoms. Fever, cough, and sore throat were the most common symptoms. High C-reactive protein levels were seen in 15 (30%) children. There was no mortality.
CONCLUSION
The disease burden appears high in lower socio-economic group with majority having a positive household contact. Milder disease pattern in the pediatric age group is reiterated.
目的
评估大流行早期儿科住院 COVID-19 患者的流行病学和临床特征。
方法
研究了 2020 年 4 月 1 日至 5 月 20 日期间通过 RT-PCR 检测 SARS-CoV-2 鼻咽拭子阳性的 1 个月至 18 岁儿童的临床和实验室特征及结局。
结果
共纳入 50 例（56%为男性）中位（IQR）年龄为 6（2-12）岁的儿童。大多数（56%）来自库帕斯瓦米上层和下层社会经济阶层的家庭。45 例（90%）有阳性家庭接触，33 例（66%）家庭拥挤。29 例（58%）儿童无症状，20 例（40%）有轻度症状。发热、咳嗽和咽痛是最常见的症状。15 例（30%）儿童的 C 反应蛋白水平升高。无死亡病例。
结论
在社会经济地位较低的人群中，疾病负担似乎较高，大多数有阳性家庭接触。在儿科年龄组中，疾病模式更温和。
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