Bristol Royal Hospital for Children, Bristol, UK.
Birmingham Children's Hospital, Birmingham, UK.
Bone Joint J. 2020 Aug;102-B(8):1048-1055. doi: 10.1302/0301-620X.102B8.BJJ-2020-0131.R1.
The Fassier Duval (FD) rod is a third-generation telescopic implant for children with osteogenesis imperfecta (OI). Threaded fixation enables proximal insertion without opening the knee or ankle joint. We have reviewed our combined two-centre experience with this implant.
In total, 34 children with a mean age of five years (1 to 14) with severe OI have undergone rodding of 72 lower limb long bones (27 tibial, 45 femoral) for recurrent fractures with progressive deformity despite optimized bone health and bisphosphonate therapy. Data were collected prospectively, with 1.5 to 11 years follow-up.
A total of 24 patients (33%) required exchange of implants (14 femora and ten tibiae) including 11 rods bending with refracture. Four (5%) required reoperation with implant retention. Loss of proximal fixation in the femur and distal fixation in the tibia were common. Four patients developed coxa vara requiring surgical correction. In total, 13 patients experienced further fractures without rod bending; eight required implant revision. There was one deep infection. The five-year survival rate, with rod revision as the endpoint, was 63% (95% confidence interval (CI) 44% to 77%) for femoral rods, with a mean age at implantation of 4.8 years (1.3 to 14.8), and 64% (95% CI 36% to 82%) for tibial rods, with a mean age at implantation of 5.2 years (2.0 to 13.8).
FD rods are easier to implant but do not improve on the revision rates reported for second generation T-piece rods. Proximal femoral fixation is problematic in younger children with a partially ossified greater trochanter. Distal tibial fixation typically fails after two years. Future generation implants should address proximal femoral and distal tibial fixation to avoid the majority of complications in this series. Cite this article: 2020;102-B(8):1048-1055.
法赛迪瓦尔(FD)棒是第三代用于成骨不全症(OI)儿童的可伸缩植入物。螺纹固定可实现近端插入,而无需打开膝关节或踝关节。我们回顾了我们在这一植入物方面的联合两中心经验。
共有 34 名年龄在 1 至 14 岁的严重 OI 儿童,因反复骨折和进行性畸形而接受了 72 根下肢长骨(27 根胫骨,45 根股骨)的 rod 手术,尽管进行了优化的骨健康和双膦酸盐治疗。数据是前瞻性收集的,随访 1.5 至 11 年。
共有 24 名患者(33%)需要更换植入物(14 根股骨和 10 根胫骨),其中 11 根棒弯曲并再次骨折。4 名患者(5%)需要保留植入物再次手术。股骨近端固定丢失和胫骨远端固定丢失很常见。4 名患者发生髋内翻,需要手术矫正。共有 13 名患者发生了无棒弯曲的进一步骨折,其中 8 名需要植入物翻修。有 1 例深部感染。以棒修改为终点,股骨棒的 5 年生存率为 63%(95%置信区间(CI)为 44%至 77%),植入时的平均年龄为 4.8 岁(1.3 至 14.8),胫骨棒的 5 年生存率为 64%(95%CI 为 36%至 82%),植入时的平均年龄为 5.2 岁(2.0 至 13.8)。
FD 棒更容易植入,但不能改善第二代 T 型棒报告的修改率。在部分骨化的大转子的年幼儿童中,股骨近端固定存在问题。胫骨远端固定通常在两年后失效。未来几代的植入物应解决股骨近端和胫骨远端的固定问题,以避免本系列中大多数并发症。
2020;102-B(8):1048-1055。