Assad Salman, Nolte Justin, Singh Dharampreet, Hanif Samrina, Ferguson Paul
Department of Neurology, Marshall University School of Medicine, Huntington, WV, USA.
Case Rep Neurol Med. 2020 Jul 15;2020:7197230. doi: 10.1155/2020/7197230. eCollection 2020.
Infarction or ischemia of the spinal cord is a rare entity and is often misdiagnosed as inflammatory myelopathy in acute settings. Atherosclerotic disease can affect spinal arteries, leading to cord ischemia with clinical presentation mixed with myelopathy. We present a case of a 66-year-old male who came to the hospital with unsteady gait and numbness of all extremities without associated pain for the past 48 hours. The neurological examination on admission directed the diagnosis towards myelopathy of the cervical spine. However, the initial magnetic resonance imaging (MRI) of the cervical spine demonstrated gliosis and restricted diffusion of the cord with multilevel neuroforaminal stenosis but without central canal stenosis or cord compression. The MRI brain, cerebrospinal fluid analysis, and rheumatologic evaluation were unremarkable. Four days into the clinical course, the patient developed weakness and spasticity of all extremities prompting further evaluation. Computed tomography angiography (CTA) scan of the head and neck revealed right vertebral artery occlusion and intracranial atherosclerotic disease. He was started on aspirin and clopidogrel for secondary risk reduction. The hospital course was further complicated by Ogilvie syndrome (OS), and the patient underwent uncomplicated cecostomy.
脊髓梗死或缺血是一种罕见的病症,在急性期常被误诊为炎性脊髓病。动脉粥样硬化疾病可影响脊髓动脉,导致脊髓缺血,临床表现与脊髓病相混合。我们报告一例66岁男性患者,在过去48小时内出现步态不稳和四肢麻木,无相关疼痛,前来我院就诊。入院时的神经系统检查将诊断指向颈椎脊髓病。然而,颈椎的初始磁共振成像(MRI)显示脊髓胶质增生和弥散受限,伴有多节段神经孔狭窄,但无中央管狭窄或脊髓受压。脑部MRI、脑脊液分析和风湿学评估均无异常。临床病程第4天,患者出现四肢无力和痉挛,促使进一步评估。头颈部计算机断层血管造影(CTA)扫描显示右椎动脉闭塞和颅内动脉粥样硬化疾病。开始给予阿司匹林和氯吡格雷以降低二次风险。奥吉尔维综合征(OS)使住院病程进一步复杂化,患者接受了顺利的盲肠造口术。