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细菌性脑膜炎后的小儿听力阈值

Pediatric Hearing Thresholds Post-bacterial Meningitis.

作者信息

Jatto Mercy E, Adeyemo Adebolajo A, Ogunkeyede Segun A, Lagunju Ikeoluwa A, Nwaorgu Onyekwere G

机构信息

Department of Otorhinolaryngology, University College Hospital, Ibadan, Nigeria.

Institute of Child Health, College of Medicine, University of Ibadan, Ibadan, Nigeria.

出版信息

Front Surg. 2020 Jul 9;7:36. doi: 10.3389/fsurg.2020.00036. eCollection 2020.

Abstract

Disabling hearing loss as a sequela of bacterial meningitis results from damage to the auditory system. This study was designed to ascertain the hearing thresholds in survivors of bacterial meningitis and the risk factors of hearing loss in childhood bacterial meningitis. One hundred and two children admitted and treated for bacterial meningitis were recruited prospectively along with 102 age- and sex-matched controls who had auditory evaluation using otoacoustic emission and auditory brain stem response tests 48 h prior to hospital discharge. This was also repeated at the follow-up clinic at 1 month after hospital discharge, irrespective of the initial hearing assessment results. There were 57 (55.9%) males and 45 (44.1%) females among the cases (mean age, 5.34 ± 4.40 years) and 55 (53.9%) males and 47 (46.1%) females among the controls (mean age, 5.31 ± 3.15 years). The prevalence of hearing loss was 30.4% among the cases, while it was 6.9% among the controls. The risk factors of hearing impairment in this study were the presence of anemia, leukocytosis, and hypoglycorrhachia. Hearing impairment with varying degrees of severity is a frequent complication of bacterial meningitis in children.

摘要

作为细菌性脑膜炎后遗症的致残性听力损失是由听觉系统受损所致。本研究旨在确定细菌性脑膜炎幸存者的听力阈值以及儿童细菌性脑膜炎听力损失的危险因素。前瞻性招募了102名因细菌性脑膜炎入院并接受治疗的儿童,以及102名年龄和性别匹配的对照儿童,后者在出院前48小时使用耳声发射和听觉脑干反应测试进行了听力评估。无论初始听力评估结果如何,出院后1个月在随访门诊也重复进行了此项评估。病例组中有57名(55.9%)男性和45名(44.1%)女性(平均年龄5.34±4.40岁),对照组中有55名(53.9%)男性和47名(46.1%)女性(平均年龄5.31±3.15岁)。病例组中听力损失的患病率为30.4%,而对照组中为6.9%。本研究中听力障碍的危险因素为贫血、白细胞增多和脑脊液糖降低。不同程度的听力障碍是儿童细菌性脑膜炎常见的并发症。

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