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前交叉韧带重建术后再次手术的发生率及预测因素:一项 6 年随访研究。

Incidence and Predictors of Subsequent Surgery After Anterior Cruciate Ligament Reconstruction: A 6-Year Follow-up Study.

机构信息

Investigation performed at Vanderbilt University Medical Center, Nashville, Tennessee, USA.

出版信息

Am J Sports Med. 2020 Aug;48(10):2418-2428. doi: 10.1177/0363546520935867.

Abstract

BACKGROUND

The cause of subsequent surgery after anterior cruciate ligament (ACL) reconstruction varies, but if risk factors for specific subsequent surgical procedures can be identified, we can better understand which patients are at greatest risk.

PURPOSE

To report the incidence and types of subsequent surgery that occurred in a cohort of patients 6 years after their index ACL reconstruction and to identify which variables were associated with the incidence of patients undergoing subsequent surgery after their index ACL reconstruction.

STUDY DESIGN

Cohort study; Level of evidence, 2.

METHODS

Patients completed a questionnaire before their index ACL surgery and were followed up at 2 and 6 years. Patients were contacted to determine whether any underwent additional surgery since baseline. Operative reports were obtained, and all surgical procedures were categorized and recorded. Logistic regression models were constructed to predict which patient demographic and surgical variables were associated with the incidence of undergoing subsequent surgery after their index ACL reconstruction.

RESULTS

The cohort consisted of 3276 patients (56.3% male) with a median age of 23 years. A 6-year follow-up was obtained on 91.5% (2999/3276) with regard to information on the incidence and frequency of subsequent surgery. Overall, 20.4% (612/2999) of the cohort was documented to have undergone at least 1 subsequent surgery on the ipsilateral knee 6 years after their index ACL reconstruction. The most common subsequent surgical procedures were related to the meniscus (11.9%), revision ACL reconstruction (7.5%), loss of motion (7.8%), and articular cartilage (6.7%). Significant risk factors for incurring subsequent meniscus-related surgery were having a medial meniscal repair at the time of index surgery, reconstruction with a hamstring autograft or allograft, higher baseline Marx activity level, younger age, and cessation of smoking. Significant predictors of undergoing subsequent surgery involving articular cartilage were higher body mass index, higher Marx activity level, reconstruction with a hamstring autograft or allograft, meniscal repair at the time of index surgery, or a grade 3/4 articular cartilage abnormality classified at the time of index ACL reconstruction. Risk factors for incurring subsequent surgery for loss of motion were younger age, female sex, low baseline Knee injury and Osteoarthritis Outcome Score symptom subscore, and reconstruction with a soft tissue allograft.

CONCLUSION

These findings can be used to identify patients who are at the greatest risk of incurring subsequent surgery after ACL reconstruction.

摘要

背景

前交叉韧带(ACL)重建后进行后续手术的原因各不相同,但如果能够确定特定后续手术程序的风险因素,我们就能更好地了解哪些患者的风险最大。

目的

报告一组患者在 ACL 重建后 6 年时发生的后续手术的发生率和类型,并确定哪些变量与 ACL 重建后患者进行后续手术的发生率相关。

研究设计

队列研究;证据等级,2 级。

方法

患者在 ACL 手术前完成了一份问卷,并在术后 2 年和 6 年进行了随访。联系患者以确定他们在基线后是否进行了任何其他手术。获取手术报告,并对所有手术程序进行分类和记录。构建逻辑回归模型,以预测哪些患者的人口统计学和手术变量与 ACL 重建后进行后续手术的发生率相关。

结果

该队列包括 3276 名患者(56.3%为男性),平均年龄为 23 岁。在 2999 名(91.5%)患者中获得了关于 ACL 重建后 6 年时发生的后续手术的发生率和频率的信息。总体而言,20.4%(612/2999)的患者在 ACL 重建后 6 年时在同侧膝关节上至少进行了 1 次后续手术。最常见的后续手术程序与半月板(11.9%)、ACL 重建翻修(7.5%)、运动丧失(7.8%)和关节软骨(6.7%)有关。发生半月板相关手术的显著危险因素是在指数手术时进行内侧半月板修复、使用腘绳肌腱自体移植物或同种异体移植物重建、较高的基线 Marx 活动水平、较年轻的年龄和戒烟。进行关节软骨相关后续手术的显著预测因素是较高的体重指数、较高的 Marx 活动水平、使用腘绳肌腱自体移植物或同种异体移植物重建、在指数手术时进行半月板修复或在 ACL 重建时分类为 3/4 级的关节软骨异常。运动丧失后续手术的危险因素是较年轻的年龄、女性、较低的基线膝关节损伤和骨关节炎结果评分症状子评分,以及使用软组织同种异体移植物重建。

结论

这些发现可用于识别 ACL 重建后发生后续手术风险最高的患者。

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