Department of Emergency (Chemical Injure Treatment Center), Jinshan Hospital, 12478Fudan University, Shanghai, China.
Department of Emergency, Second People's Hospital, Pinghu, Zhejiang, China.
Toxicol Ind Health. 2020 Oct;36(10):750-758. doi: 10.1177/0748233720945184. Epub 2020 Aug 6.
Hydrogen sulfide poisoning can cause severe myocardial injury, but the damage is subtle and can be easily misdiagnosed. This report presents the dynamic observation of myocardial injury associated with hydrogen sulfide poisoning.
Two young men presented with symptoms of "lightning-like" death immediately after entering a tank. They were found and rescued in 20 min at a time when they were already in a coma. Case 1 had no spontaneous breathing and pulse, while case 2 had spontaneous breathing and a pulse. Upon transfer to a local hospital, case 1 received continuous cardiopulmonary resuscitation which led to the recovery of his heart rate 3 min after arriving at the hospital. However, the patient remained in a Glasgow coma scale of 3. He was transferred to our hospital where he, unfortunately, died on the seventh day due to multiple organ failure. Case 2 was also transferred to the intensive care unit in our hospital and on the fourth day of hospitalization, the patient presented ST-segment elevation and dynamic changes in markers of myocardial injury. Changes in electrocardiogram and markers of myocardial injury were monitored and examination improved through conventional echocardiography, coronary artery CT, radionuclide myocardial perfusion imaging, and two-dimensional speckle tracking imaging strain. The treatment gradually improved the patient's myocardial injury and was discharged from the hospital.
Hydrogen sulfide poisoning can cause damage to myocardial function and the damage can be more insidious in nature and with a delayed onset. Recovery from myocardial damage can be very slow.
硫化氢中毒可导致严重的心肌损伤,但损伤细微,容易误诊。本报告介绍了与硫化氢中毒相关的心肌损伤的动态观察。
两名年轻男子在进入罐内后立即出现“闪电样”死亡症状。他们在昏迷 20 分钟后被发现并获救。病例 1 无自主呼吸和脉搏,病例 2 有自主呼吸和脉搏。在转移到当地医院后,病例 1 接受了持续心肺复苏,在到达医院 3 分钟后心率恢复。然而,患者仍处于格拉斯哥昏迷量表 3 级。他被转至我院,但不幸于第 7 天因多器官衰竭死亡。病例 2 也被转至我院重症监护病房,在住院第 4 天,患者出现 ST 段抬高和心肌损伤标志物的动态变化。监测心电图和心肌损伤标志物的变化,并通过常规超声心动图、冠状动脉 CT、放射性核素心肌灌注成像和二维斑点追踪成像应变进行检查。治疗逐渐改善了患者的心肌损伤,患者出院。
硫化氢中毒可导致心肌功能受损,损伤性质更隐匿,发病时间延迟。心肌损伤的恢复可能非常缓慢。