Garg Bhawan Deep, Bansal Anju, Kabra Nandkishor S
J Perinat Educ. 2020 Jul 1;29(3):123-133. doi: 10.1891/J-PE-D-18-00043. Epub 2020 Jun 23.
Neonatal hyperbilirubinemia (NNH) is the most common clinical sign seen in neonatal practice. Kangaroo mother care (KMC), a new strategy has been tried for the management of hyperbilirubinemia.
To evaluate the role of KMC for reduction of bilirubin and duration of phototherapy in term and preterm neonates.
The literature search was done for various randomized control trials by searching the Cochrane Central Register of Controlled Trials, PubMed, EMBASE, ongoing clinical trials and abstracts of conferences.
This review included five RCTs that fulfilled inclusion criteria. Out of five trials, two trials reported a significant reduction in bilirubin and three trials reported a significant reduction in duration of phototherapy.
KMC may be a novel strategy in the management of NNH. However, due to small sample size and heterogeneity between the trials, the current evidence is not sufficient. Hence, large trials with adequate sample sizes are needed.
新生儿高胆红素血症(NNH)是新生儿科最常见的临床症状。袋鼠式护理(KMC)作为一种新策略已被尝试用于高胆红素血症的治疗。
评估袋鼠式护理在足月儿和早产儿中降低胆红素水平及缩短光疗时间的作用。
通过检索Cochrane对照试验中央注册库、PubMed、EMBASE、正在进行的临床试验和会议摘要,对各种随机对照试验进行文献检索。
本综述纳入了5项符合纳入标准的随机对照试验。在这5项试验中,2项试验报告胆红素水平显著降低,3项试验报告光疗时间显著缩短。
袋鼠式护理可能是新生儿高胆红素血症治疗中的一种新策略。然而,由于样本量小且试验间存在异质性,目前证据不足。因此,需要进行样本量充足的大型试验。