Suppr超能文献

医学体重管理期间的体重减轻并不预示着减重手术后的体重减轻:一项回顾性队列研究。

Weight loss during medical weight management does not predict weight loss after bariatric surgery: a retrospective cohort study.

机构信息

Department of Bariatric Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom; Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, United Kingdom.

Birmingham Medical School, University of Birmingham, Birmingham, United Kingdom.

出版信息

Surg Obes Relat Dis. 2020 Nov;16(11):1723-1730. doi: 10.1016/j.soard.2020.06.049. Epub 2020 Jul 4.

Abstract

BACKGROUND

Many bariatric surgical centers mandate achieving weight loss targets through medical weight management (MWM) programs before offering bariatric surgery, but the evidence for this is unclear.

OBJECTIVES

To examine the relationship between weight changes during (1) MWM, and (2) preoperative low-energy-diet (LED), and weight changes at 12 and 24 months after surgery.

SETTING

Multicenter community- and acute-based MWM services referring to one regional bariatric center, United Kingdom.

METHODS

A retrospective cohort study of patients who attended MWM and then underwent a primary laparoscopic bariatric procedure (adjustable gastric banding [LAGB], or Roux-en-Y gastric bypass [RYGB]) in a single bariatric center in the United Kingdom between 2013 and 2015. Data were collected from patient electronic records.

RESULTS

Two hundred eight patients were included (LAGB n = 128, RYGB n = 80). Anthropometric data were available for 94.7% and 88.0% of participants at 12 and 24 months, respectively. There was no relationship between weight loss during MWM and after surgery at either 12 or 24 months. Weight loss during the preoperative LED predicted greater weight loss after LAGB (β = .251, P = .006) and less weight loss after RYGB (β = -.390, P = .003) at 24 months, after adjusting for age, sex, ethnicity, baseline weight, and LED duration.

CONCLUSIONS

Weight loss in MWM does not predict greater weight loss outcomes up to 24 months after LAGB or RYGB. Greater weight loss during the preoperative LED predicted greater weight loss after LAGB and less weight loss after RYGB. Our results suggest that patients should not be denied bariatric surgery because of not achieving weight loss in MWM. Weight loss responses to preoperative LEDs as a predictor of postsurgical weight loss requires further investigation.

摘要

背景

许多减重手术中心要求在提供减重手术之前通过医学体重管理(MWM)计划达到减肥目标,但这方面的证据并不清楚。

目的

检查(1)MWM 期间和(2)术前低能量饮食(LED)期间体重变化与手术后 12 个月和 24 个月体重变化之间的关系。

设置

英国一家区域性减重中心的多中心社区和急性 MWM 服务机构。

方法

对 2013 年至 2015 年间在英国一家减重中心接受 MWM 治疗并随后接受腹腔镜初次减重手术(可调节胃束带术[LAGB]或 Roux-en-Y 胃旁路术[RYGB])的患者进行回顾性队列研究。数据从患者电子病历中收集。

结果

共纳入 208 例患者(LAGB 组 n = 128,RYGB 组 n = 80)。分别有 94.7%和 88.0%的参与者在 12 个月和 24 个月时可提供体重数据。MWM 期间的减重与手术后 12 个月或 24 个月时的减重均无相关性。术前 LED 期间的减重预测 LAGB 术后减重更多(β=0.251,P=0.006)和 RYGB 术后减重更少(β=-0.390,P=0.003),调整年龄、性别、种族、基线体重和 LED 持续时间后仍有统计学意义。

结论

MWM 期间的减重并不能预测 LAGB 或 RYGB 术后 24 个月时的减重结果。术前 LED 期间的减重越多,LAGB 术后的减重越多,RYGB 术后的减重越少。我们的结果表明,不应该因为患者在 MWM 期间没有达到减肥目标而拒绝为其进行减重手术。术前 LED 作为术后减重的预测指标,其减重反应需要进一步研究。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验