蓟（Cynara cardunculus var. altilis）苞片的生物活性特性和酚类成分的季节性变化。
Seasonal variation in bioactive properties and phenolic composition of cardoon (Cynara cardunculus var. altilis) bracts.
机构信息
Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal; Grupo de Investigación en Polifenoles (GIP-USAL), Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno s/n, 37007 Salamanca, Spain.
University of Thessaly, Department of Agriculture, Crop Production and Rural Environment, 38446, N. Ionia, Volos, Greece.
出版信息
Food Chem. 2021 Jan 30;336:127744. doi: 10.1016/j.foodchem.2020.127744. Epub 2020 Aug 5.
Cardoon (Cynara cardunculus L.) bracts were collected at different maturation stages to investigate seasonal changes in the phenolic compounds profile and in vitro bioactivities. Among the 12 phenolic compounds tentatively identified, 3,5-O-dicaffeoylquinic acid (21.83 mg/g extract) and apigenin-7-O-glucuronide (10.6 mg/g extract) were the most abundant. Immature bracts (C1: principal growth stage (PGS) 5) had the highest phenolic compounds content, and anti-inflammatory (IC = 72 µg/mL) and cytotoxic (GI of 30-79 µg/mL) activities. Moreover, extract C1 inhibited efficiently the formation of thiobarbituric acid reactive substances (TBARS; IC = 26.8 µg/mL), while extract C8 (PGS 8/9) was more effective against oxidative haemolysis (IC 38 and 75 µg/mL). The highest antibacterial and antifungal activities were attributed to samples C1 and C6 (PGS 7/8) and samples C2 (PGS 5/6) and C4 (PGS 6/7), respectively. Overall, the obtained results suggest the seasonal changes of polyphenolic composition and bioactivity of cardoon bracts of variable maturity.
蓟（Cynara cardunculus L.）的苞片在不同的成熟阶段被收集，以研究酚类化合物谱和体外生物活性的季节性变化。在12 种被推测的酚类化合物中，3,5-O-二咖啡酰奎宁酸（21.83mg/g 提取物）和芹菜素-7-O-葡萄糖醛酸苷（10.6mg/g 提取物）含量最丰富。未成熟的苞片（C1：主要生长阶段（PGS）5）酚类化合物含量最高，具有抗炎（IC=72μg/mL）和细胞毒性（GI 在 30-79μg/mL 之间）活性。此外，提取物 C1 能有效抑制硫代巴比妥酸反应物质（TBARS）的形成（IC=26.8μg/mL），而提取物 C8（PGS 8/9）对氧化溶血的抑制作用更强（IC 38 和 75μg/mL）。最高的抗菌和抗真菌活性归因于样品 C1 和 C6（PGS 7/8）和样品 C2（PGS 5/6）和 C4（PGS 6/7）。总的来说，研究结果表明，不同成熟度的蓟苞片的多酚组成和生物活性存在季节性变化。
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