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利用支气管肺泡灌洗术检测艾滋病患者的病原微生物

Pathogenic microorganism detection in AIDS patients using bronchoalveolar lavage fluid.

作者信息

Shi Jinchuan, Zhang Zhongdong, Wang Mengyan, Zhao Chenfei, Yan Jun, Liu Shourong, Yu Jianhua, Zhu Mingli

机构信息

Department of Second Infectious Disease, Xixi Hospital of Hangzhou Hangzhou, China.

Graduate School, Zhejiang Chinese Medical University Hangzhou, China.

出版信息

Int J Clin Exp Pathol. 2020 Jul 1;13(7):1727-1732. eCollection 2020.

Abstract

This study aimed to investigate the use of fiberoptic bronchoscopy and bronchoalveolar lavage in the diagnosis of pulmonary pathogenic microorganism infection in AIDS patients. We retrospectively analyzed the clinical data, fiberoptic bronchoscopy and bronchoalveolar lavage fluid laboratory examinations of 209 AIDS patients with pulmonary infection. Among 209 patients, we found 42 cases of mycobacterial infection, 3 cases of bacterial infection, 58 cases of pneumocystis carinii pneumonia (PCP), 27 cases that were fungal positive, 99 cases of CMV, and 103 cases positive for GM test of which 83 cases were considered positive. BALF pathogen distribution was related to CD4+ T lymphocyte count. The primary pathogens of pulmonary infection in AIDS patients were cytomegalovirus, , fungi, and . Fiberoptic bronchoscopy and bronchoalveolar lavage are important in the diagnosis of pathogenic microorganisms in lung infections of AIDS patients.

摘要

本研究旨在探讨纤维支气管镜检查及支气管肺泡灌洗在艾滋病患者肺部致病微生物感染诊断中的应用。我们回顾性分析了209例艾滋病肺部感染患者的临床资料、纤维支气管镜检查及支气管肺泡灌洗液体实验室检查结果。在209例患者中,我们发现42例分枝杆菌感染、3例细菌感染、58例卡氏肺孢子虫肺炎(PCP)、27例真菌阳性、99例巨细胞病毒(CMV)感染以及103例GM试验阳性,其中83例被认为是阳性。支气管肺泡灌洗(BALF)病原体分布与CD4 + T淋巴细胞计数有关。艾滋病患者肺部感染的主要病原体是巨细胞病毒、真菌等。纤维支气管镜检查及支气管肺泡灌洗在艾滋病患者肺部感染致病微生物的诊断中具有重要作用。

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Pathogenic microorganism detection in AIDS patients using bronchoalveolar lavage fluid.
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