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术后谵妄:为何、如何以及如何在你的机构应对它。

Postoperative delirium: why, what, and how to confront it at your institution.

机构信息

Department of Anesthesia & Perioperative Care, University of California, San Francisco, San Francisco, California, USA.

出版信息

Curr Opin Anaesthesiol. 2020 Oct;33(5):668-673. doi: 10.1097/ACO.0000000000000907.

Abstract

PURPOSE OF REVIEW

The current article reviews the importance of postoperative delirium (POD), focusing on the older surgical population, and summarizes the best-practice guidelines about POD prevention and treatment which have been published within the last several years. We also describe our local experience with implementing a perioperative delirium risk stratification and prevention pathway, and review implementation science principles which others may find useful as they move toward risk stratification and prevention in their own institutions.

RECENT FINDINGS

There are few areas of consensus, backed by strong experimental data, in POD best-practice guidelines. Most guidelines recommend preoperative cognitive screening, nonpharmacologic delirium prevention measures, and avoidance of deliriogenic medications. The field of implementation science offers strategies for closing the evidence-practice gap, which we supplement with lessons learned from our own experience implementing a perioperative delirium risk stratification and prevention pathway.

SUMMARY

POD continues to be a serious perioperative complication commonly experienced by older adults. Growing appreciation of its prognostic implications and evidence behind multidisciplinary, collaborative, and focused prevention strategies rooted in implementation science have prompted several major groups to issue consensus guidelines. Adopting best practices POD risk stratification and prevention pathways will improve perioperative care for older adults.

摘要

目的综述

本文回顾了术后谵妄(POD)的重要性,重点关注老年手术人群,并总结了过去几年发布的关于 POD 预防和治疗的最佳实践指南。我们还描述了我们在实施围手术期谵妄风险分层和预防途径方面的本地经验,并回顾了实施科学原则,其他机构在实施风险分层和预防时可能会发现这些原则有用。

最新发现

在 POD 最佳实践指南中,只有少数几个领域存在共识,并有强有力的实验数据支持。大多数指南建议进行术前认知筛查、非药物性谵妄预防措施,并避免使用致谵妄药物。实施科学领域提供了缩小证据与实践差距的策略,我们还从我们自己实施围手术期谵妄风险分层和预防途径的经验中吸取了教训。

总结

POD 仍然是老年人常见的严重围手术期并发症。对其预后意义的认识不断提高,以及基于实施科学的多学科、协作和集中预防策略的证据,促使几个主要团体发布了共识指南。采用最佳的 POD 风险分层和预防途径将改善老年人的围手术期护理。

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