Chen Yi-Bo, Wang Zhao-Hui, Fu Gui-Ming, Wan Quan-Xin, Li Xiao-Jing, Chen Jin
Department of Head and Neck Oncology, Sichuan Cancer Hospital, Chengdu 610041, People's Republic of China.
Cancer Manag Res. 2020 Aug 5;12:6887-6894. doi: 10.2147/CMAR.S246576. eCollection 2020.
To evaluate the application of computer-aided design (CAD) and three-dimensional (3D) visualization techniques in the diagnosis and treatment of refractory thyroid tumors.
The clinical data from 12 cases of refractory thyroid tumors treated with CAD and 3D visualization techniques from September 2016 to January 2018 were analyzed retrospectively. Ten cases were malignant, while two cases were benign. All tracheas in the 12 cases were invaded or oppressed by the thyroid tumors. Six of the cases experienced type III dyspnea, while the other six cases had type II dyspnea. All patients underwent contrast-enhanced computed tomography (CT) imaging.
CAD and 3D visualization technologies were used to guide the surgeries. Ten cases of malignant thyroid tumors underwent total thyroidectomy, cervical lymph node dissection, and invaded organ resection. Among the ten cases, five underwent sleeve resections and anastomosis reconstructions, one underwent a tracheal sleeve resection and total laryngectomy, two underwent tracheal window resections, one case underwent a sternotomy, and one case underwent a laryngopharyngectomy, invaded skin resection, and pectoralis major muscle flap reconstruction. The two cases of benign thyroid tumors underwent subtotal thyroidectomies. Using CAD and 3D visualization techniques, surgeons can visually observe the relationship of the tumor with the respiratory tract and essential blood vessels, which can lead to optimized surgical plans and improved surgical outcomes.
CAD and 3D visualization technologies have an important role in the personalized surgical intervention of thyroid cancer, which will likely have important clinical implications.
评估计算机辅助设计(CAD)和三维(3D)可视化技术在难治性甲状腺肿瘤诊断和治疗中的应用。
回顾性分析2016年9月至2018年1月采用CAD和3D可视化技术治疗的12例难治性甲状腺肿瘤的临床资料。其中10例为恶性,2例为良性。12例患者的气管均受到甲状腺肿瘤侵犯或压迫。6例患者出现Ⅲ度呼吸困难,另外6例为Ⅱ度呼吸困难。所有患者均接受了增强计算机断层扫描(CT)成像。
采用CAD和3D可视化技术指导手术。10例甲状腺恶性肿瘤患者接受了甲状腺全切除术、颈部淋巴结清扫术和受侵器官切除术。其中5例行袖状切除术和吻合重建术,1例行气管袖状切除术和全喉切除术,2例行气管开窗切除术,1例行胸骨切开术,1例行喉咽切除术、受侵皮肤切除术和胸大肌皮瓣重建术。2例甲状腺良性肿瘤患者接受了甲状腺次全切除术。使用CAD和3D可视化技术,外科医生可以直观地观察肿瘤与呼吸道和重要血管的关系,从而制定优化的手术方案并改善手术效果。
CAD和3D可视化技术在甲状腺癌的个性化手术干预中具有重要作用,可能具有重要的临床意义。