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黑种美国人与白种美国人行垂直袖状胃切除术后心血管危险因素的比较。

Cardiovascular Risk Factors Following Vertical Sleeve Gastrectomy in Black Americans Compared with White Americans.

机构信息

Department of Physiology and Biophysics, University of Mississippi Medical Center, 2500 North State St. Guyton 558, Jackson, MS, 39216, USA.

Department of Data Science, University of Mississippi Medical Center, Jackson, MS, 39216, USA.

出版信息

Obes Surg. 2021 Mar;31(3):1004-1012. doi: 10.1007/s11695-020-04938-x. Epub 2020 Aug 22.

Abstract

OBJECTIVE

Bariatric surgery presents a long-term solution for clinical obesity. Given that Black Americans (BA) carry a greater burden of obesity-related comorbidities than White Americans (WA), understanding the racial disparities regarding remission of obesity comorbidities following the most common bariatric surgery, sleeve gastrectomy (SG). The goal of the current study was to provide quantitative values related to cardiovascular and lipid outcomes following SG and determine if racial disparities exist between BA and WA.

METHODS

Data was collected from de-identified electronic medical records for patients receiving SG surgery at the University of Mississippi Medical Center in Jackson, MS, USA.

RESULTS

Of 464 patients who obtained SG from (2013-2019), 64% were WA, and 36% were BA. Before surgery, BA had significantly greater body weight (BW), body mass index (BMI), and systolic (SBP) and diastolic (DBP) blood pressures (BP) in comparison with WA. Compared with WA, BA were predicted to lose 5.1 kg less BW than WA at 1-year follow-up. Reduction in SBP (- 0.96 vs. - 0.60 mmHg/doubling of days) and DBP (- 0.51 vs. - 0.26 mmHg/doubling of days) was significantly higher in WA compared with BA. There was no racial difference in the change to total cholesterol, high-density lipoprotein (HDL)-cholesterol, low-density lipoprotein (LDL)-cholesterol, or triglycerides by race. When normalized to weight loss, the racial disparity in BP reduction was mitigated.

CONCLUSIONS

These data indicate that BA lose less body weight following SG; however, loss of excess body weight loss is associated with improvement to BP similarly in both BA and WA.

摘要

目的

减重手术为临床肥胖提供了长期解决方案。鉴于黑种美国人(BA)比白种美国人(WA)承受着更大的肥胖相关合并症负担,了解最常见的减重手术袖状胃切除术(SG)后肥胖合并症缓解的种族差异。本研究的目的是提供与 SG 后心血管和血脂结果相关的定量值,并确定 BA 和 WA 之间是否存在种族差异。

方法

数据来自美国密西西比大学医学中心杰克逊分校接受 SG 手术的患者的匿名电子病历。

结果

在 464 名接受 SG 的患者中,64%为 WA,36%为 BA。在手术前,BA 的体重(BW)、体重指数(BMI)和收缩压(SBP)和舒张压(DBP)均显著高于 WA。与 WA 相比,BA 在 1 年随访时预计会比 WA 少减轻 5.1kg 的 BW。WA 的 SBP(-0.96 与-0.60mmHg/倍增天数)和 DBP(-0.51 与-0.26mmHg/倍增天数)的下降幅度明显高于 BA。种族之间总胆固醇、高密度脂蛋白(HDL)-胆固醇、低密度脂蛋白(LDL)-胆固醇或甘油三酯的变化没有种族差异。按体重减轻进行归一化后,BP 降低的种族差异得到缓解。

结论

这些数据表明,BA 在接受 SG 后体重减轻较少;然而,超重体重减轻与 BA 和 WA 的 BP 改善相似。

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