角膜环形溃疡。
A corneal ring ulcer.
作者信息
Alhajraf Khaled, Lin Shawn R, Jacobs Deborah S
机构信息
Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
Stein Eye Institute, David Geffen School of Medicine, University of California - Los Angeles, Los Angeles, CA, USA.
出版信息
Am J Ophthalmol Case Rep. 2020 Aug 5;20:100856. doi: 10.1016/j.ajoc.2020.100856. eCollection 2020 Dec.
PURPOSE
The aim of this report is to present the case of a corneal ring ulcer that presented with diagnostic and therapeutic challenges.
OBSERVATIONS
A 52-year-old woman was referred by her retina doctors for ulceration of the left cornea and pain 8 days after intravitreal ranibizumab injection for diabetic macular edema. She had been treated with erythromycin ointment, topical moxifloxacin, and therapeutic soft contact lens, which she tolerated for less than 24 hours prior to referral. Visual acuity of the left eye was counting fingers. Slit lamp examination revealed a ring-shaped corneal ulcer.
CONCLUSIONS
Neurotrophic corneal ulceration can mimic acanthamoeba keratitis. Neurotrophic disease should be considered in patients with underlying risk factors in whom infectious etiology cannot be confirmed and/or who don't respond to anti-microbial therapy.
目的
本报告旨在介绍一例角膜环形溃疡病例，该病例在诊断和治疗方面存在挑战。
观察结果
一名52岁女性因糖尿病性黄斑水肿接受玻璃体内注射雷珠单抗8天后，被视网膜科医生转诊，其左眼角膜出现溃疡并伴有疼痛。她曾接受红霉素眼膏、局部莫西沙星治疗，并佩戴治疗性软性接触镜，但在转诊前她耐受该治疗不到24小时。左眼视力为指数。裂隙灯检查发现环形角膜溃疡。
结论
神经营养性角膜溃疡可模仿棘阿米巴角膜炎。对于存在潜在危险因素、无法确诊感染病因和/或对抗微生物治疗无反应的患者，应考虑神经营养性疾病。
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