Liao Xia, Bu Yang, Jia Qingan
Department of Nutrition, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
Department of Hepatobiliary Surgery, General Hospital, Ningxia Medical University, Yinchuan, 750001, China.
Genes Dis. 2019 Nov 2;7(3):370-379. doi: 10.1016/j.gendis.2019.10.016. eCollection 2020 Sep.
Liver cancer is the sixth most commonly diagnosed cancer and the fourth leading cause of cancer death worldwide. Western medicine and therapies are the primary treatment strategies of hepatocellular carcinoma (HCC), but the general prognosis for HCC patients is still dismal. Under these circumstances, HCC prevention is particularly important. Traditional Chinese medicine (TCM) encompasses a wealth of documented therapeutic resources, and "preventative treatment" is the principle of TCM. In China, TCM has been used for HCC prevention for thousands of years, and has also been demonstrated to be effective for the treatment of HCC in modern China. However, the TCM theory for prevention and treatment of HCC is more widely accepted in China than abroad. In this review, we first summarize the herbs and ancient formulas with therapeutic effects on HCC. We also review the research status of TCM in modern medicine as well as the current obstacles in its development. Finally, we discuss the future of TCM in the context of precision and integrated medicine. After reviewing the literature, we believe that TCM, through ancient development, is an advanced method of cancer treatment with positive curative effects, despite its surrounding controversy. Furthermore, precise analyses and systematic research methods provides novel approaches to modernize TCM for the future.
肝癌是全球第六大常见诊断癌症，也是癌症死亡的第四大主要原因。西医和疗法是肝细胞癌（HCC）的主要治疗策略，但HCC患者的总体预后仍然不容乐观。在这种情况下，HCC的预防尤为重要。中医拥有丰富的文献记载的治疗资源，“治未病”是中医的原则。在中国，中医用于HCC预防已有数千年历史，在现代中国也已被证明对HCC治疗有效。然而，中医防治HCC的理论在国内比在国外更被广泛接受。在本综述中，我们首先总结了对HCC有治疗作用的草药和古代方剂。我们还回顾了中医在现代医学中的研究现状以及其发展目前面临的障碍。最后，我们在精准医学和整合医学的背景下讨论中医的未来。在查阅文献后，我们认为，尽管存在争议，但中医经过长期发展，是一种具有积极疗效的先进癌症治疗方法。此外，精准分析和系统研究方法为中医未来的现代化提供了新途径。
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