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肺癌CT筛查的最新进展:首个主要的针对性癌症筛查项目。

An update on CT screening for lung cancer: the first major targeted cancer screening programme.

作者信息

Baldwin David R, Callister Matthew E J

机构信息

Nottingham University Hospitals and Honorary Professor, University of Nottingham, Respiratory Medicine Unit, David Evans Centre, Nottingham, United Kingdom.

St James's University Hospital, Leeds, United Kingdom.

出版信息

Br J Radiol. 2020 Dec 1;93(1116):20200636. doi: 10.1259/bjr.20200636. Epub 2020 Sep 7.

Abstract

Screening for lung cancer with low radiation dose CT has been shown to be effective in reducing lung cancer mortality by two major randomised controlled trials. Lung cancer screening is set to become the largest targeted cancer screening programme globally, but the effectiveness of the programme is dependent on many different factors. This article describes the key evidence for lung cancer screening, the key factors important for optimisation and the progress towards implementation.

摘要

两项主要的随机对照试验表明,采用低辐射剂量CT筛查肺癌可有效降低肺癌死亡率。肺癌筛查即将成为全球最大的针对性癌症筛查项目,但其成效取决于诸多不同因素。本文介绍了肺癌筛查的关键证据、优化筛查的重要关键因素以及实施过程中的进展情况。

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