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膝关节镜治疗伴骨关节炎的半月板损伤与单独物理治疗相比是否会延迟膝关节置换?

Does Knee Arthroscopy for Treatment of Meniscal Damage with Osteoarthritis Delay Knee Replacement Compared to Physical Therapy Alone?

机构信息

Department of Orthopaedic Surgery, Kaiser Permanente South Bay Medical Center, Harbor City, CA, USA.

Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA, USA.

出版信息

Clin Orthop Surg. 2020 Sep;12(3):304-311. doi: 10.4055/cios19114. Epub 2020 Jun 24.

Abstract

BACKGROUD

To determine patient factors that lead to treatment of meniscal tears with osteoarthritis (OA) with knee arthroscopy (KA) or physical therapy only (PT-only); and to assess differences in clinical outcomes including the time to knee arthroplasty.

METHODS

Patients aged ≥ 45 years with OA at meniscal tear diagnosis were followed up from the date of surgery (KA) or first PT visit (PT-only) until partial/total knee replacement surgery, death, disenrollment, or end of study. Demographic and clinical characteristics were compared and used to derive propensity scores. A Cox proportional hazards model was used to estimate the risk of knee replacement surgery and greater healthcare utilization associated with KA vs. PT-only.

RESULTS

Among 7,026 patients (KA, 69%; PT-only, 31%), 27% had partial or total knee replacement surgery during follow-up. PT-only patients were older and more likely to be women and had more comorbidities. After accounting for differences between groups, the cumulative incidence of knee replacement was modestly but significantly higher for those who received KA than those who underwent PT-only (hazard ratio, 1.30; 95% confidence interval, 1.17-1.44; < 0.001), although there was no significant difference in health service utilization, narcotic medication dispenses, or knee injections after initiating treatment.

CONCLUSIONS

For patients with meniscal damage complicated by OA, those who underwent KA were 30% more likely to have partial or total knee replacement surgery at any given time than those who had PT alone.

摘要

背景

确定导致骨关节炎(OA)伴半月板撕裂患者接受膝关节镜(KA)或仅物理治疗(PT-only)治疗的患者因素;并评估包括膝关节置换术时间在内的临床结果差异。

方法

在半月板撕裂诊断为 OA 的年龄≥45 岁的患者中,从手术(KA)或首次物理治疗就诊(PT-only)之日起随访,直至部分/全膝关节置换术、死亡、失访或研究结束。比较人口统计学和临床特征,并用于推导倾向评分。使用 Cox 比例风险模型估计与 KA 相比,PT-only 与膝关节置换手术和更多医疗保健利用相关的风险。

结果

在 7026 名患者中(KA,69%;PT-only,31%),27%在随访期间接受了部分或全膝关节置换手术。PT-only 患者年龄较大,更可能为女性,且合并症更多。在考虑到组间差异后,接受 KA 的患者比接受 PT-only 的患者膝关节置换的累积发生率略高但具有统计学显著性(风险比,1.30;95%置信区间,1.17-1.44;<0.001),尽管在开始治疗后,在卫生服务利用、阿片类药物配给或膝关节注射方面没有显著差异。

结论

对于伴有 OA 的半月板损伤患者,与单独接受 PT 治疗的患者相比,接受 KA 的患者在任何给定时间行部分或全膝关节置换术的可能性增加 30%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4777/7449858/8ed3cabb807b/cios-12-304-g001.jpg

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