Emerging disease epidemiology unit, Institut Pasteur, Paris, France.
PACRI unit, Conservatoire National des Arts et Métiers, Paris, France.
Nat Rev Immunol. 2020 Oct;20(10):583-584. doi: 10.1038/s41577-020-00451-5.
Herd immunity is a key concept for epidemic control. It states that only a proportion of a population needs to be immune (through overcoming natural infection or through vaccination) to an infectious agent for it to stop generating large outbreaks. A key question in the current COVID-19 pandemic is how and when herd immunity can be achieved and at what cost.
群体免疫是控制传染病的一个关键概念。它指出,对于一种传染病,只有一部分人群(通过自然感染或接种疫苗获得免疫力)需要具有免疫力,才能阻止其引发大规模疫情。当前 COVID-19 大流行中的一个关键问题是如何以及何时可以实现群体免疫,以及需要付出什么代价。