通用药物依从性量表（GMAS）阿拉伯语版本在沙特慢性病患者中的翻译与验证
Translation and validation of the Arabic version of the General Medication Adherence Scale (GMAS) in Saudi patients with chronic illnesses.
作者信息
Naqvi Atta Abbas, Mahmoud Mansour Adam, AlShayban Dhfer Mahdi, Alharbi Fawaz Abdullah, Alolayan Sultan Othman, Althagfan Sultan, Iqbal Muhammad Shahid, Farooqui Maryam, Ishaqui Azfar Athar, Elrggal Mahmoud E, Haseeb Abdul, Hassali Mohamed Azmi
机构信息
Department of Pharmacy Practice, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Department of Clinical and Hospital Pharmacy, College of Pharmacy, Taibah University, Al-Madinah Al-Munawarah, Saudi Arabia.
出版信息
Saudi Pharm J. 2020 Sep;28(9):1055-1061. doi: 10.1016/j.jsps.2020.07.005. Epub 2020 Jul 31.
PURPOSE
The study aimed to translate and validate the Arabic version of General Medication Adherence Scale (GMAS) in Saudi patients with chronic diseases.
METHODS
A multi-center cross sectional study was conducted for a month in out-patient wards of hospitals in Khobar, Dammam, Makkah, and Madinah, Saudi Arabia. Patients were randomly selected from a registered patient pools at hospitals and the item-subject ratio was kept at 1:20. The tool was assessed for factorial, construct, convergent, known group and predictive validities as well as, reliability and internal consistency of scale were also evaluated. Sensitivity, specificity, and accuracy were also evaluated. Data were analyzed using SPSS v24 and MedCalc v19.2. The study was approved by concerned ethics committees (IRB-129-25/6/1439) and (IRB-2019-05-002).
RESULTS
A total of 282 responses were received. The values for normed fit index (NFI), comparative fit index (CFI), Tucker Lewis index (TLI) and incremental fit index (IFI) were 0.960, 0.979, 0.954 and 0.980. All values were >0.95. The value for root mean square error of approximation (RMSEA) was 0.059, i.e., <0.06. Hence, factorial validity was established. The average factor loading of the scale was 0.725, i.e., >0.7, that established convergent validity. Known group validity was established by obtaining significant p-value <0.05, for the associations based on hypotheses. Cronbach's α was 0.865, i.e., >0.7. Predictive validity was established by evaluating odds ratios (OR) of demographic factors with adherence score using logistic regression. Sensitivity was 78.16%, specificity was 76.85% and, accuracy of the tool was 77.66%, i.e., >70%.
CONCLUSION
The Arabic version of GMAS achieved all required statistical parameters and was validated in Saudi patients with chronic diseases.
目的
本研究旨在翻译并验证通用药物依从性量表（GMAS）阿拉伯语版本在沙特慢性病患者中的有效性。
方法
在沙特阿拉伯胡拜尔、达曼、麦加和麦地那的医院门诊病房进行了为期一个月的多中心横断面研究。患者从医院登记的患者库中随机选取，项目与受试者比例保持在1:20。对该工具进行了因子效度、结构效度、收敛效度、已知群体效度和预测效度评估，同时还评估了量表的信度和内部一致性。还评估了敏感性、特异性和准确性。使用SPSS v24和MedCalc v19.2进行数据分析。该研究获得了相关伦理委员会（IRB - 129 - 25/6/1439）和（IRB - 2019 - 05 - 002）的批准。
结果
共收到282份回复。规范拟合指数（NFI）、比较拟合指数（CFI）、塔克·刘易斯指数（TLI）和增量拟合指数（IFI）的值分别为0.960、0.979、0.954和0.980。所有值均>0.95。近似误差均方根（RMSEA）值为0.059，即<0.06。因此，确立了因子效度。量表的平均因子载荷为0.725，即>0.7，确立了收敛效度。基于假设的关联获得了显著的p值<0.05，从而确立了已知群体效度。克朗巴赫α系数为0.865，即>0.7。通过使用逻辑回归评估人口统计学因素与依从性得分的比值比（OR）确立了预测效度。敏感性为78.16%，特异性为76.85%，该工具的准确性为77.66%，即>70%。
结论
GMAS阿拉伯语版本达到了所有所需的统计参数，并在沙特慢性病患者中得到了验证。
Zotero 插件