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血友病患者的足部健康相关生活质量:病例对照研究。

Foot health-related quality of life in hemophiliacs: A case-control study.

机构信息

Department Nursing and Podiatry, Faculty of Health Sciences, University of Málaga, c/ Arquitecto Francisco Peñalosa 3, Ampliación del Campus de Teatinos, 29071 Málaga, Spain, Instituto de Investigación Biomédica de Málaga (IBIMA) https://orcid.org/000-0002-8634-7114.

Research, Health and Podiatry Group. Department of Health Sciences, Faculty of Nursing and Podiatry. Universidade da Coruña, Ferrol, Spain.

出版信息

Int J Med Sci. 2020 Aug 29;17(15):2396-2401. doi: 10.7150/ijms.48705. eCollection 2020.

Abstract

Haemophilia is considered as a chronic genetic disease related with alteration in coagulation mechanism which affects to health related quality of life (HQoL). The goal compared marks of HQoL, in haemophiliacs with respect non haemophilic subjects. A population of 74 subjects, were recruited from association of haemophilic illness separated in haemophilic subjects (n = 37) and no haemophilic (n = 37). For subjects who suffered haemophilia were enlisted from the association of haemophilic illness after a seminar of 45 minutes to them and to their relatives about foot health. Control subjects, were recruited from their relatives who live with the patient. The marks of the Foot Health Status Questionnaire Spanish S_FHSQ sub-scales were recompiled. Results: All S_FHSQ domains as foot pain, foot function, tootwear, general foot health, general health, physical activity and social capacity showed lower scores in the haemophilic than non-haemophilic group ( <0.01) except for vigour ( = 0.173). Regarding the rest sub-scale marks of S_FHSQ, showed no significant difference <0.01. Subjects with a haemophilia showed significant worse foot QoL in all S_FHSQ domains except vigour domain compared with non-haemophilic subjects.

摘要

血友病被认为是一种与凝血机制改变相关的慢性遗传性疾病,会影响健康相关生活质量(HQoL)。本研究旨在比较血友病患者和非血友病患者的 HQoL 评分。招募了 74 名受试者,其中血友病组 37 名,非血友病组 37 名。对血友病患者进行了 45 分钟的足部健康讲座,之后从血友病协会招募他们及其亲属作为研究对象。对照组的亲属作为对照,与患者共同生活。重编译了西班牙 S_FHSQ 足部健康状况问卷的子量表的分数。结果:除活力外(= 0.173),所有 S_FHSQ 领域的足部疼痛、足部功能、鞋类、足部整体健康、整体健康、身体活动和社会能力评分在血友病组均低于非血友病组( <0.01)。关于 S_FHSQ 的其余子量表评分,差异无统计学意义( <0.01)。与非血友病患者相比,血友病患者在所有 S_FHSQ 领域的足部 QoL 均显著较差,除活力领域外。

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