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难治性先天性乳糜腹水:纤维蛋白胶在其治疗中的作用

Refractory Congenital Chylous Ascites: Role of Fibrin Glue in its Management.

作者信息

Saxena Rahul, Suchiang Biangchwadaka, Pathak Manish, Sinha Arvind

机构信息

Department of Pediatric Surgery, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

出版信息

J Indian Assoc Pediatr Surg. 2020 Jul-Aug;25(4):245-247. doi: 10.4103/jiaps.JIAPS_123_19. Epub 2020 Jun 24.

Abstract

Chylous ascites is the accumulation of triglyceride-rich lymph in the abdomen. Its occurrence during the infantile period is quite rare. Congenital chylous ascites (CCA) is one, which occurs in children <3 months of age, due to maldevelopment of the lymphatic system. There is no clearly defined treatment protocol for CCA; however, the use of medium-chain triglycerides (MCT)-based diet or total parenteral nutrition (TPN) with octreotide has been successful. Failure of conservative management, however, leads to surgical exploration to deal with those leaking lymphatics. In our case, we had initially given a trial of managing the child with MCT-based diet followed by a TPN along with octreotide. However, the failure of both leads us to operate the child during which we incorporated the use of fibrin glue over the leaking mesenteric lymphatic vesicles, which ultimately led to the resolution of the chylous ascites.

摘要

乳糜性腹水是腹部富含甘油三酯的淋巴液积聚。其在婴儿期的发生相当罕见。先天性乳糜性腹水(CCA)是其中一种,发生于3个月以下的儿童,病因是淋巴系统发育不良。目前尚无明确的CCA治疗方案;然而,使用基于中链甘油三酯(MCT)的饮食或联合奥曲肽的全胃肠外营养(TPN)已取得成功。然而,保守治疗失败会导致进行手术探查以处理那些渗漏的淋巴管。在我们的病例中,我们最初尝试用基于MCT的饮食管理患儿,随后联合TPN及奥曲肽。然而,两者均失败,这促使我们为患儿进行手术,术中我们在渗漏的肠系膜淋巴囊上使用了纤维蛋白胶,最终使乳糜性腹水得以消退。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc83/7478288/2eec4dde1d61/JIAPS-25-245-g001.jpg

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