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探索新西兰首发精神病中本土少数民族的不平等现象——一项全国队列研究。

Exploring indigenous ethnic inequities in first episode psychosis in New Zealand - A national cohort study.

机构信息

Department of Public Health, University of Otago Wellington, PO Box 7343, Newtown, Wellington 6242, New Zealand; Māori/Indigenous Health Institute (MIHI), University of Otago Christchurch, PO Box 4345, Christchurch 8140, New Zealand.

Department of Public Health, University of Otago Wellington, PO Box 7343, Newtown, Wellington 6242, New Zealand.

出版信息

Schizophr Res. 2020 Sep;223:311-318. doi: 10.1016/j.schres.2020.09.004. Epub 2020 Sep 15.

Abstract

INTRODUCTION

First episode psychosis (FEP) disproportionately affects rangatahi (young) Māori, the Indigenous people of New Zealand, but little is known about factors contributing to this inequity. This study describes a cohort of rangatahi Māori and young non-Māori with FEP, and explores ethnic differences in incidence rates, and the contribution of deprivation, urbanicity and substance use.

METHODS

Māori and young non-Māori, aged 13-25 at the time of the first recorded psychosis-related diagnoses, were identified from within Statistics NZ's Integrated Data Infrastructure (IDI), between 2009 and 2012. To estimate age-standardised FEP incidence rates, the population-at-risk was estimated using IDI-based usual resident population estimates for 2009-2012, stratified by ethnicity and single year of age. Poisson regression models were used to estimate ethnic differences in FEP incidence adjusted for age, gender, deprivation, and urban-rural area classification.

RESULTS

A total of 2412 young people with FEP (40% Māori, 60% non-Māori) were identified. Māori were younger, and more likely to live in deprived and rural communities and be diagnosed with schizophrenia. Substance induced psychosis was uncommon. The unadjusted age-standardised FEP incidence rate ratio was 2.48 (95% CI: 2.29-2.69) for rangatahi Māori compared with young non-Māori. While adjusting for age, sex, deprivation and urban rural area classification reduced ethnic differences in incidence, rangatahi Māori were still more than twice as likely to have been diagnosed with FEP compared to young non-Māori.

CONCLUSIONS

This study confirms previous findings of elevated rates of psychosis among rangatahi Māori. The difference in rates between Māori and non-Māori were attenuated but remained after adjustment for deprivation and urbanicity.

摘要

简介

首发精神分裂症(FEP)不成比例地影响新西兰原住民毛利青年,但导致这种不公平现象的因素知之甚少。本研究描述了一组首发精神分裂症的毛利青年和年轻非毛利人,并探讨了发病率的种族差异,以及贫困、城市化和物质使用的影响。

方法

从 2009 年至 2012 年,在新西兰统计局的综合数据基础设施(IDI)中,确定了年龄在 13-25 岁之间首次出现与精神疾病相关诊断的毛利青年和年轻非毛利人。为了估计年龄标准化的 FEP 发病率,使用 IDI 基于 2009-2012 年的常用居民人口估计值,按种族和单一年龄分层,来估计发病风险人群。使用泊松回归模型,在调整年龄、性别、贫困和城乡地区分类后,估计 FEP 发病率的种族差异。

结果

共确定了 2412 名首发精神分裂症的年轻人(40%毛利人,60%非毛利人)。毛利青年更年轻,更有可能生活在贫困和农村社区,并被诊断为精神分裂症。物质诱导的精神病并不常见。未经调整的年龄标准化 FEP 发病率比为毛利青年 2.48(95%CI:2.29-2.69),与年轻非毛利人相比。虽然调整了年龄、性别、贫困和城乡分类,但仍减少了发病率的种族差异,但毛利青年被诊断为 FEP 的可能性仍然是非毛利青年的两倍多。

结论

本研究证实了之前毛利青年精神分裂症发病率升高的发现。在调整贫困和城市化因素后,毛利人和非毛利人之间的发病率差异仍然存在。

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