在儿童局限性硬皮病（硬斑病）中使用弹性成像超声的可行性。
Feasibility of Using Elastography Ultrasound in Pediatric Localized Scleroderma (Morphea).
作者信息
Pérez Manuela, Zuccaro Jennifer, Mohanta Arun, Tijerin Marta, Laxer Ronald, Pope Elena, Doria Andrea S
机构信息
Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada.
Division of Plastic and Reconstructive Surgery, The Hospital for Sick Children, Toronto, Ontario, Canada; Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
出版信息
Ultrasound Med Biol. 2020 Dec;46(12):3218-3227. doi: 10.1016/j.ultrasmedbio.2020.08.007. Epub 2020 Sep 18.
Assessment and monitoring of inflammation and tissue damage is crucial in localized scleroderma (LS), but validated diagnostic tools are lacking. We aimed to determine the feasibility of using acoustic radiation force imaging ultrasound elastography in the assessment of pediatric-onset LS lesions. Conventional ultrasound and shear-wave elastography (SWE) imaging were used to characterize changes in pre-assigned LS lesions in 13 prospectively recruited participants. Contralateral sites were used as controls. Mean SWE values were compared. LS lesions were significantly stiffer than control sites in the dermis and the hypodermis using both parametric and non-parametric tests, before and after skin-thickness normalization. We show that SWE imaging is a feasible way to discriminate between normal skin and LS lesions in the pediatric population.
炎症和组织损伤的评估与监测在局限性硬皮病（LS）中至关重要，但缺乏经过验证的诊断工具。我们旨在确定使用声辐射力成像超声弹性成像评估儿童期发病的LS病变的可行性。采用传统超声和剪切波弹性成像（SWE）对13名前瞻性招募参与者预先指定的LS病变变化进行特征分析。对侧部位用作对照。比较平均SWE值。在皮肤厚度标准化前后，使用参数检验和非参数检验均显示，LS病变在真皮和皮下组织中的硬度明显高于对照部位。我们表明，SWE成像对于区分儿科人群中的正常皮肤和LS病变是一种可行的方法。
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