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肥胖与心房颤动:我们应该对肥胖个体进行心房颤动筛查吗?一项全面综述。

Obesity and Atrial Fibrillation: Should We Screen for Atrial Fibrillation in Obese Individuals? A Comprehensive Review.

作者信息

Ghattas Kyrillos N, Ilyas Shahbakht, Al-Refai Reham, Maharjan Reeju, Diaz Bustamante Liliana, Khan Safeera

机构信息

Internal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.

Surgery, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.

出版信息

Cureus. 2020 Sep 15;12(9):e10471. doi: 10.7759/cureus.10471.

Abstract

Obesity and obesity-related illnesses (ORIs) constitute a significant burden on the healthcare system, with a very high prevalence in the general population. Atrial fibrillation (AF) is the most common arrhythmia seen by healthcare providers. The risk of AF in obese individuals is reported to be high and in correlation with Body Mass Index (BMI), leading to the high prevalence of AF in the general population and the expected epidemic of AF to come. Greater left atrial dimensions and left atrial remodeling together form the AF substrate in the obese population along with the role of epicardial adipose tissue (EAT) in inducing inflammation and fibrosis of the atrial myocardium and thus facilitating the onset of AF. In our paper, we reviewed the literature published on the link between obesity and AF, as well as the potential behind new management approaches. Multiple studies have explored different approaches, either conventional or novel. Considering the impact of prevention in medicine nowadays, we proposed a screening practice for AF in obese individuals. More research is needed to acquire a comprehensive protocol for the management of AF in the obese population that can be applied by primary healthcare providers to combat this evolving matter.

摘要

肥胖及肥胖相关疾病(ORIs)给医疗系统带来了沉重负担,在普通人群中的患病率极高。心房颤动(AF)是医疗服务提供者所见到的最常见的心律失常。据报道,肥胖个体患AF的风险很高,且与体重指数(BMI)相关,这导致AF在普通人群中的高患病率以及预计未来AF的流行趋势。更大的左心房尺寸和左心房重构与心外膜脂肪组织(EAT)在诱发心房心肌炎症和纤维化从而促进AF发作方面的作用共同构成了肥胖人群中的AF基质。在我们的论文中,我们回顾了关于肥胖与AF之间联系以及新管理方法背后潜力的已发表文献。多项研究探索了不同的方法,包括传统方法和新方法。考虑到当今预防在医学中的影响,我们提出了针对肥胖个体进行AF筛查的做法。需要更多研究来获得一套全面的肥胖人群AF管理方案,以便初级医疗服务提供者能够应用该方案来应对这一不断发展的问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9614/7494408/490aa5d4224b/cureus-0012-00000010471-i01.jpg

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