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[通过多重检测免疫细胞化学法评估迟发型超敏反应。一项确定样本人群参考值的多中心研究]

[Evaluation of the delayed hypersensitivity response by the Multitest-IMC. Multicenter study for the definition of reference values in a sample population].

作者信息

Dionigi R, Berti Riboli E, Bertoglio S, Bonoldi A P, Braga M, Brandi L S, Coccaglio R, Corazza G R, Craus W, Cristallo M

出版信息

Minerva Med. 1987 Jun 15;78(11):721-31.

PMID:3295598
Abstract

The latest investigations in the field of clinical immunology have proposed ways of assessing immunological efficiency that have also been used to identify patients most susceptible to infectious complications. The assessment of delayed hypersensitivity response (DHR) using anamnestic antigens is currently the most common method. The results of a polycentric study are presented. The study was conducted on a group of healthy subjects from various Italian regions divided into three age classes. Positive responses to the MT were noted in 96.4% of the population studied. The incidence of energy was statistically higher among females than males, while the mean response to the MT expressed in millimetres was statistically higher in males. Though 7 antigens were administered, the responsive population reacted on average to 3. The highest incidence of positive responses was to Candida, with Trichophyton responsible for the fewest.

摘要

临床免疫学领域的最新研究提出了评估免疫效率的方法,这些方法也被用于识别最易发生感染性并发症的患者。目前,使用回忆性抗原评估迟发型超敏反应(DHR)是最常用的方法。本文呈现了一项多中心研究的结果。该研究针对来自意大利不同地区的一组健康受试者开展,这些受试者被分为三个年龄组。在所研究的人群中,96.4% 的人对结核菌素(MT)呈阳性反应。女性的能量反应发生率在统计学上高于男性,而以毫米表示的对MT的平均反应在男性中统计学上更高。尽管使用了7种抗原,但有反应的人群平均对3种抗原产生反应。阳性反应发生率最高的是念珠菌,毛癣菌引起的反应最少。

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