Human erythrocyte glutathione S-transferase: a possible marker of chemical exposure.
作者信息
Ansari G A, Singh S V, Gan J C, Awasthi Y C
出版信息
Toxicol Lett. 1987 Jun;37(1):57-62. doi: 10.1016/0378-4274(87)90167-6.
PMID:3296321
Abstract
We have explored the possibility of using glutathione S-transferase (GST) as a biological marker of chemical exposure. All the model compounds tested in the present study (acrolein, propylene oxide, styrene oxide, ethylene dibromide and ethylene dichloride) showed a dose-dependent inactivation of erythrocyte GST in situ as well as the inhibition of purified erythrocyte GST.
摘要
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