新冠疫情期间的睡眠与免疫力
Sleep and immunity in times of COVID-19.
作者信息
Silva Eduardo de Sousa Martins E, Ono Ben Hur Vitor Silva, Souza José Carlos
机构信息
. Universidade Federal do Triângulo Mineiro (UFTM), Uberaba, MG, Brasil.
. Universidade para o Desenvolvimento do Estado e da Região do Pantanal (Uniderp), Campo Grande, MS, Brasil.
出版信息
Rev Assoc Med Bras (1992). 2020 Sep 21;66Suppl 2(Suppl 2):143-147. doi: 10.1590/1806-9282.66.S2.143. eCollection 2020.
BACKGROUND
Analyze how the COVID-19 (SARS-CoV-2) pandemic and its social restriction measures affect sleep quality and the immunological system.
METHODS
An integrative bibliographical review was carried out using scientific articles from the last five years, from the PUBMED databases, with the descriptors: Sleep; Quarantine; COVID-19; Immunity; Mental Health. Besides the books "Oxford textbook of sleep disorders", "Cellular and molecular immunology", and "Treaty of Infectology".
RESULTS
Sleep affects immunity. This happens through the regulation of immunological markers and their cells. Therefore, the COVID-19 pandemic can promote sleep disturbances and harm the immune system function.
CONCLUSION
Sleep exercises a direct influence on immunity maintenance and immunological response. Circadian rhythm alterations, associated with the psychological problems imposed by the COVID-19 pandemic compromise the quality of sleep and, for that reason, the immune system.
背景
分析2019冠状病毒病（SARS-CoV-2）大流行及其社会限制措施如何影响睡眠质量和免疫系统。
方法
使用过去五年来自PUBMED数据库的科学文章进行综合文献综述，描述词为：睡眠；隔离；2019冠状病毒病；免疫；心理健康。此外还参考了《牛津睡眠障碍教科书》《细胞与分子免疫学》和《传染病学条约》等书籍。
结果
睡眠影响免疫。这是通过免疫标志物及其细胞的调节实现的。因此，2019冠状病毒病大流行可导致睡眠障碍并损害免疫系统功能。
结论
睡眠对免疫维持和免疫反应有直接影响。与2019冠状病毒病大流行带来的心理问题相关的昼夜节律改变会损害睡眠质量，进而影响免疫系统。
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