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中文版强迫性药物使用量表:在门诊美沙酮维持治疗项目中的验证。

The Chinese version of obsessive compulsive drug use scale: validation in outpatient methadone maintenance treatment program.

机构信息

Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Shanghai Pudong New Area Mental Health Center, Tongji University School of Medicine, Shanghai, China.

出版信息

BMC Psychiatry. 2020 Sep 25;20(1):465. doi: 10.1186/s12888-020-02843-2.

Abstract

BACKGROUND

The Obsessive Compulsive Drug Use Scale (OCDUS) measures the overall craving level within a period from a multidimensional perspective. However, no studies have addressed the validity of the new OCDUS factor structure, presented in 2016, in China. Additionally, there is lack of evidence on the interaction among risk factors for relapse. We aimed to assess the psychometric properties of the scores of the Chinese version of the OCDUS in patients with heroin dependence receiving methadone maintenance treatment (MMT). Further, we aimed to assess the correlations of the OCDUS scores with withdrawal symptoms, depression, anxiety, and nicotine dependence.

METHODS

We enrolled 113 adults (age 32-64 years) and administered them with the OCDUS, Subjective Opioid Withdrawal Scale (SOWS), Beck Depression Inventory-II (BDI-II), State-Trait Anxiety Inventory (STAI), and Fagerstrom Test for Nicotine Dependence (FTND).

RESULTS

Exploratory factor analysis identified a 3-dimensional component that included "Frequency of craving," "Inference of heroin," and "Control of heroin." These factors showed acceptable internal consistency, adequate item-total correlations, and significant item-subscale correlations. There was no correlation between the OCUDS scores and age, education, duration of receiving MMT, and MMT dosages. However, there was a significant correlation between the OCDUS total scores and the SOWS, STAI, BDI-II, and FTND scores. The scores of all the subscales were associated with the SOWS scores; further, the scores of the first two subscales were associated with BDI-II scores while only the scores of the first subscale were associated with the FTND scores.

CONCLUSIONS

Our findings support the reliability and structure validity of the OCDUS scores. Heroin craving, withdrawal symptoms, negative emotions, and nicotine dependence, which are considered as risk factors for heroin relapse, might interact with each other. There is a need for further studies on the underlying mechanism of these clinical phenomena.

摘要

背景

《强迫性药物使用量表》(OCDUS)从多维角度衡量一个时期内的整体渴求程度。然而,目前还没有研究探讨 2016 年提出的 OCDUS 新因子结构在中国的有效性。此外,缺乏关于复发风险因素相互作用的证据。我们旨在评估接受美沙酮维持治疗(MMT)的海洛因依赖患者中文版 OCDUS 评分的心理测量特性。此外,我们旨在评估 OCDUS 评分与戒断症状、抑郁、焦虑和尼古丁依赖之间的相关性。

方法

我们纳入了 113 名年龄在 32-64 岁的成年人,并对他们进行了 OCDUS、主观阿片戒断量表(SOWS)、贝克抑郁量表-II(BDI-II)、状态特质焦虑量表(STAI)和尼古丁依赖 Fagerstrom 测试(FTND)的评估。

结果

探索性因素分析确定了包括“渴求频率”、“推断海洛因”和“控制海洛因”在内的 3 个维度组成部分。这些因子显示出可接受的内部一致性、充分的项目总分相关性以及显著的项目子量表相关性。OCDUS 评分与年龄、教育程度、接受 MMT 的时间长短以及 MMT 剂量之间无相关性。然而,OCDUS 总分与 SOWS、STAI、BDI-II 和 FTND 评分之间存在显著相关性。所有子量表的评分都与 SOWS 评分相关;此外,前两个子量表的评分与 BDI-II 评分相关,而仅第一个子量表的评分与 FTND 评分相关。

结论

我们的研究结果支持 OCDUS 评分的可靠性和结构有效性。被认为是海洛因复发风险因素的海洛因渴求、戒断症状、负面情绪和尼古丁依赖可能相互作用。需要进一步研究这些临床现象的潜在机制。

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Validation of the cocaine versions of the Obsessive Compulsive Drug Use Scale and the Desires for Drug Questionnaire.
Am J Drug Alcohol Abuse. 2015;41(4):358-65. doi: 10.3109/00952990.2015.1043210. Epub 2015 May 26.
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