镁离子在核酶系统中的作用。
Role of Mg2+ in the ribozyme system.
作者信息
Toh H, Imamura A, Kanda K
出版信息
FEBS Lett. 1987 Jul 27;219(2):279-82. doi: 10.1016/0014-5793(87)80235-1.
PMID:3301401
Abstract
Recently, several kinds of catalytic activities have been identified from L-19 IVS RNA or 'ribozyme'. In the catalytic process of ribozyme, Mg2+ is required. We investigated the role of Mg2+ by molecular orbital calculation. Based on the results of the calculation, a model for the self-splicing reaction was constructed.
摘要
最近，已从L-19 IVS RNA或“核酶”中鉴定出几种催化活性。在核酶的催化过程中，需要Mg2+。我们通过分子轨道计算研究了Mg2+的作用。基于计算结果，构建了一个自我剪接反应模型。
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