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研究 COVID-19(SARS-CoV-2)在感染新冠病毒患者汗液中的存在情况。

Study presence of COVID-19 (SARS-CoV-2) in the sweat of patients infected with Covid-19.

机构信息

Department of Microbiology and Immunology, Kashan University of Medical Sciences, Kashan, Iran.

Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

Microb Pathog. 2020 Dec;149:104556. doi: 10.1016/j.micpath.2020.104556. Epub 2020 Oct 5.

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease, which started in Wuhan, Chin, has now become a public health challenge in most countries around the world. Proper preventive measures are necessary to prevent the spread of the virus to help control the pandemic. Because, SARS-CoV-2 is new, its transmission route has not been fully understood. In this study, we aimed to investigate the presence of SARS-CoV-2 in the sweat secretion of COVID-19 patients. Sweat specimens of 25 COVID- 19 patients were collected and tested for SARS-CoV-2 RNA by Real-time Polymerase Chain Reaction (RT-PCR) method. After RNA extraction and cDNA amplification, all samples were examined for the presence of ORF-1ab and N genes related to COVID-19. Results annotated by Realtime PCR machines software based on Dynamic algorithm. The results of this study showed the absence of SARS-CoV-2 in the sweat samples taken from the foreheads of infected people. Therefore, it can be concluded that the sweat of patients with COVID- 19 cannot transmit SARS-CoV-2. However they can be easily contaminated with other body liquids.

摘要

严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)疾病始于中国武汉,现已成为世界大多数国家的公共卫生挑战。需要采取适当的预防措施来防止病毒传播,以帮助控制大流行。因为 SARS-CoV-2 是新的,其传播途径尚未完全了解。在这项研究中,我们旨在调查 COVID-19 患者的汗液中是否存在 SARS-CoV-2。采集了 25 例 COVID-19 患者的汗液标本,并通过实时聚合酶链反应(RT-PCR)方法检测 SARS-CoV-2 RNA。在提取 RNA 和 cDNA 扩增后,使用与 COVID-19 相关的 ORF-1ab 和 N 基因对所有样本进行检测。基于动态算法的 Realtime PCR 机器软件注释结果。这项研究的结果表明,从感染者额头上采集的汗液样本中未检测到 SARS-CoV-2。因此,可以得出结论,COVID-19 患者的汗液不能传播 SARS-CoV-2。然而,它们很容易被其他体液污染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e57/7534876/627ba079f784/gr1_lrg.jpg

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