每周分割剂量放射治疗老年不可切除的头颈部皮肤鳞状细胞癌。

Weekly hypofractionated radiation therapy in elderly non-resectable cutaneous squamous cell carcinoma of the head and neck region.

机构信息

Department of Radiotherapy, Policlinico Umberto I "Sapienza" University of Rome, Viale Regina Elena 326, 00161, Rome, Italy.

出版信息

Radiol Med. 2021 Apr;126(4):620-622. doi: 10.1007/s11547-020-01260-5. Epub 2020 Oct 15.

DOI:10.1007/s11547-020-01260-5

PMID:33058025

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8007498/

Abstract

INTRODUCTION

Treatment of inoperable cutaneous squamous cell carcinoma (cSCC) of the head and neck region is still debated.

CASE REPORT

We report an original case of cure of cSCC of the head and neck region with weekly hypofractionated radiation therapy with megavoltage electrons prescribed for locally advanced inoperable disease.

RESULTS

Weekly hypofractionated radiotherapy assured complete regression and was well-tolerated.

CONCLUSION

The real efficacy of this treatment in the therapeutic arsenal remains to be defined. A clinical trial is ongoing to test the use of 8 weekly fractions of 8 Gy hypofractionated RT regimens in non-resectable cSCC cases.

摘要