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一名从未接受过通气治疗、肺部健康的新冠病毒肺炎患者先后出现双侧自发性气胸的病例报告。

Case report of sequential bilateral spontaneous pneumothorax in a never-ventilated, lung-healthy COVID-19-patient.

作者信息

Caviezel Claudio, Weiss Lina, Haessig Gabriela, Alfaré Christian, Haberecker Martina, Varga Zsuzsanna, Frauenfelder Thomas, Opitz Isabelle

机构信息

Department of Thoracic Surgery, University Hospital Zurich, Switzerland.

Department of Thoracic Surgery, University Hospital Zurich, Switzerland.

出版信息

Int J Surg Case Rep. 2020;75:441-445. doi: 10.1016/j.ijscr.2020.09.148. Epub 2020 Sep 24.

Abstract

INTRODUCTION

Patients with COVID-19 infection and severe lung parenchyma alterations may need mechanical ventilation with subsequent pneumothorax and eventually persistent air leak in case of pre-existing lung disease.

PRESENTATION OF CASE

This report presents the case of a never-ventilated 58 years old male patient without pre-existing, underlying lung disease demonstrating severe lung parenchyma changes due to COVID-19-pneumonia. He suffered from recurrent bilateral spontaneous pneumothoraces, which were successfully treated with bilateral thoracoscopy and resections of the destroyed lung areas. Notably, he has already been under treatment with anticoagulation due to portal thrombosis 8 years ago.

DISCUSSION

Although especially know from patients under mechanical ventilation, this patient suffered from spontaneous pneumothorax without ever been ventilated. Probably due to the severe vascular inflammatory changes and focal endothelitis like also seen in other organs of COVID-19 patients, the pneumothorax may lead to a prolonged air leak, which needs surgical therapy. The patients pre-existing anticoagulation therapy may prevented him from a mere severe course.

CONCLUSION

Early surgical therapy may be considered in COVID-19 patients with persistent air leak, even if not mechanically ventilated. Simultaneously, the role of early anticoagulation needs further investigation.

摘要

引言

新型冠状病毒肺炎(COVID-19)感染且伴有严重肺实质改变的患者可能需要机械通气,继而发生气胸,若患者原有肺部疾病,则最终可能出现持续性漏气。

病例介绍

本报告介绍了一名58岁男性患者的病例,该患者既往无肺部基础疾病,从未接受过机械通气,因COVID-19肺炎出现严重肺实质改变。他反复发生双侧自发性气胸,通过双侧胸腔镜检查及对毁损肺组织区域的切除得以成功治疗。值得注意的是,该患者8年前因门静脉血栓形成已接受抗凝治疗。

讨论

尽管自发性气胸尤其多见于接受机械通气的患者,但该患者从未接受过机械通气却发生了自发性气胸。可能由于在COVID-19患者的其他器官中也可见到的严重血管炎性改变和局灶性内皮炎,气胸可能导致持续性漏气,这需要手术治疗。患者先前的抗凝治疗可能避免了病情仅发展为重症。

结论

对于存在持续性漏气的COVID-19患者,即使未接受机械通气,也可考虑早期手术治疗。同时,早期抗凝治疗的作用需要进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/355f/7527682/c5d3b6c73c4d/gr1.jpg

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