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精准医学时代的分子乳腺癌成像。

Molecular Breast Cancer Imaging in the Era of Precision Medicine.

机构信息

Department of Radiology and Imaging Sciences, Division of Nuclear Medicine and Molecular Imaging, Emory University Hospital, 1364 Clifton Rd, Atlanta, GA 30322.

出版信息

AJR Am J Roentgenol. 2020 Dec;215(6):1512-1519. doi: 10.2214/AJR.20.22883. Epub 2020 Oct 21.

DOI:10.2214/AJR.20.22883
PMID:33084364
Abstract

Precision medicine in oncology aims to individualize the patient's treatment and management regimen according to the accurate assessment of diagnosis, risk of recurrence, or progression. In this review, we will discuss the evolving role of molecular imaging (breast-specific gamma imaging and positron emission mammography) toward precision medicine in patients with breast cancer. Incorporating molecular imaging for breast cancer will lead to precision medicine, which holds promise to facilitate appropriate personalized treatment in patients with breast cancer.

摘要

肿瘤精准医学旨在根据对诊断、复发或进展风险的精确评估,为患者制定个体化的治疗和管理方案。在这篇综述中,我们将讨论分子成像(乳腺专用伽玛成像和正电子发射乳房 X 线摄影术)在乳腺癌精准医学中的作用。将分子成像纳入乳腺癌将带来精准医学,有望为乳腺癌患者提供合适的个体化治疗。

相似文献

1
Molecular Breast Cancer Imaging in the Era of Precision Medicine.精准医学时代的分子乳腺癌成像。
AJR Am J Roentgenol. 2020 Dec;215(6):1512-1519. doi: 10.2214/AJR.20.22883. Epub 2020 Oct 21.
2
Molecular Imaging and Precision Medicine in Breast Cancer.乳腺癌中的分子成像与精准医学
PET Clin. 2017 Jan;12(1):39-51. doi: 10.1016/j.cpet.2016.08.001. Epub 2016 Oct 4.
3
Role of positron emission tomography/computed tomography in breast cancer.正电子发射断层扫描/计算机断层扫描在乳腺癌中的作用。
Radiol Clin North Am. 2013 Sep;51(5):781-98. doi: 10.1016/j.rcl.2013.06.003.
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PET/Computed Tomography in Breast Cancer: Can It Aid in Developing a Personalized Treatment Design?乳腺癌中的正电子发射断层扫描/计算机断层扫描:它能否有助于制定个性化治疗方案?
PET Clin. 2016 Jul;11(3):297-303. doi: 10.1016/j.cpet.2016.02.006. Epub 2016 Apr 20.
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Preclinical Molecular Imaging for Precision Medicine in Breast Cancer Mouse Models.临床前分子成像在乳腺癌小鼠模型精准医学中的应用
Contrast Media Mol Imaging. 2019 Sep 22;2019:8946729. doi: 10.1155/2019/8946729. eCollection 2019.
6
Positron Emission Tomography (PET) and breast cancer in clinical practice.正电子发射断层扫描(PET)与临床实践中的乳腺癌
Eur J Radiol. 2009 Jan;69(1):50-8. doi: 10.1016/j.ejrad.2008.07.039. Epub 2008 Sep 23.
7
Background ¹⁸F-FDG uptake in positron emission mammography (PEM): correlation with mammographic density and background parenchymal enhancement in breast MRI.¹⁸F-FDG 摄取在正电子发射型乳腺断层摄影术(PEM)中的应用:与乳腺 MRI 中的乳腺密度和背景实质增强的相关性。
Eur J Radiol. 2013 Oct;82(10):1738-42. doi: 10.1016/j.ejrad.2013.05.016. Epub 2013 Jun 24.
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Diagnostic Value of Nineteen Different Imaging Methods for Patients with Breast Cancer: a Network Meta-Analysis.19种不同影像学方法对乳腺癌患者的诊断价值:一项网状Meta分析
Cell Physiol Biochem. 2018;46(5):2041-2055. doi: 10.1159/000489443. Epub 2018 Apr 28.
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A preliminary report of breast cancer screening by positron emission mammography.正电子发射乳腺断层成像用于乳腺癌筛查的初步报告。
Ann Nucl Med. 2016 Feb;30(2):130-7. doi: 10.1007/s12149-015-1040-0. Epub 2015 Nov 19.
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Newly-Developed Positron Emission Mammography (PEM) Device for the Detection of Small Breast Cancer.用于检测小乳腺癌的新开发正电子发射乳腺断层显像(PEM)设备。
Tohoku J Exp Med. 2018 May;245(1):13-19. doi: 10.1620/tjem.245.13.

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Ann Nucl Med. 2025 Jun 26. doi: 10.1007/s12149-025-02071-2.
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Breast incidentaloma: Cardiac PET readers beware.乳腺偶发瘤:心脏PET阅片者请注意。
Radiol Case Rep. 2024 Dec 2;20(2):1141-1144. doi: 10.1016/j.radcr.2024.10.152. eCollection 2025 Feb.
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Future Directions in the Assessment of Axillary Lymph Nodes in Patients with Breast Cancer.
乳腺癌患者腋窝淋巴结评估的未来方向。
Medicina (Kaunas). 2023 Aug 25;59(9):1544. doi: 10.3390/medicina59091544.
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Application of Breast Scintigraphy for Patients with Suspicious (Breast Imaging-Reporting and Data System IV) Breast Lesions.乳腺闪烁扫描术在可疑(乳腺影像报告和数据系统IV级)乳腺病变患者中的应用。
Adv Biomed Res. 2023 Apr 25;12:86. doi: 10.4103/abr.abr_347_21. eCollection 2023.
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Deep learning for differentiating benign from malignant tumors on breast-specific gamma image.基于乳腺特异性γ图像的良恶性肿瘤深度学习鉴别
Technol Health Care. 2023;31(S1):61-67. doi: 10.3233/THC-236007.
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PET-CT in Clinical Adult Oncology: II. Primary Thoracic and Breast Malignancies.PET-CT在临床成人肿瘤学中的应用:II. 原发性胸部和乳腺恶性肿瘤
Cancers (Basel). 2022 May 29;14(11):2689. doi: 10.3390/cancers14112689.
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Imaging Surveillance Options for Individuals With a Personal History of Breast Cancer: Expert Panel Narrative Review.具有乳腺癌个人病史者的影像学监测选择:专家小组叙事性综述。
AJR Am J Roentgenol. 2022 Dec;219(6):854-868. doi: 10.2214/AJR.22.27635. Epub 2022 May 11.
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Radioiodinated Ethinylestradiol Derivatives for Estrogen Receptor Targeting Breast Cancer Imaging.用于雌激素受体靶向乳腺癌成像的放射性碘化乙炔雌二醇衍生物
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Advances and Future Directions in Molecular Breast Imaging.分子乳腺成像的进展与未来方向。
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