Chan Zuckerberg Biohub, San Francisco, CA 94158, United States of America.
Department of Physics, University of Washington, Seattle, WA 98115, United States of America.
Phys Biol. 2020 Oct 21;17(6):065010. doi: 10.1088/1478-3975/abb209.
Shelter-in-place and other confinement strategies implemented in the current COVID-19 pandemic have created stratified patterns of contacts between people: close contacts within households and more distant contacts between the households. The epidemic transmission dynamics is significantly modified as a consequence. We introduce a minimal model that incorporates these household effects in the framework of mean-field theory and numerical simulations. We show that the reproduction number R depends on the household size in a surprising way: linearly for relatively small households, and as a square root of size for larger households. We discuss the implications of the findings for the lockdown, test, tracing, and isolation policies.
就地避难和其他在当前 COVID-19 大流行中实施的隔离策略在人与人之间产生了分层的接触模式:家庭内部的密切接触和家庭之间的远距离接触。因此,传染病传播动力学发生了显著变化。我们在平均场理论和数值模拟的框架中引入了一个最小模型,该模型将这些家庭效应纳入其中。我们表明,繁殖数 R 以一种令人惊讶的方式取决于家庭规模:对于相对较小的家庭是线性的,对于较大的家庭则是规模的平方根。我们讨论了这些发现对封锁、测试、追踪和隔离政策的影响。