关于正常人下食管括约肌胃内pH值与压力之间的关系。
On the relationship between gastric pH and pressure in the normal human lower oesophageal sphincter.
作者信息
Kaye M D
出版信息
Gut. 1979 Jan;20(1):59-63. doi: 10.1136/gut.20.1.59.
Abstract
The effect upon the lower oesophageal sphincter (LOS) of acid in the proximal stomach was investigated in 12 young healthy subjects. The cardia was perfused in turn with solutions at pH 7, 4, 3, 2, and 1, during successive withdrawals of three perfused pressure-recording catheters, openings of which were at the same axial level. Although there was considerable individual variation, there was a direct and significant relationship between LOW pressure and the acidity of the solution perfused. The results suggest that resting LOS pressure and the acidity of the solution perfused. The results suggest that resting LOS pressure may be determined in part by the pH of the gastric content.
摘要
在12名年轻健康受试者中研究了近端胃内的酸对食管下括约肌（LOS）的影响。在依次回撤三根灌注压力记录导管（其开口处于同一轴向水平）的过程中，依次用pH值为7、4、3、2和1的溶液灌注贲门。尽管个体差异很大，但低压与灌注溶液的酸度之间存在直接且显著的关系。结果表明静息LOS压力与灌注溶液的酸度有关。结果表明，静息LOS压力可能部分由胃内容物的pH值决定。
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