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[Correlation between EGLN1 gene, protein express in lung tissue of rats and pulmonary artery pressure at different altitude].
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Salidroside rescues hypoxic cardiomyocytes by regulating the EGLN1/HIF‑1α pathway.
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Reply to Liu et al.: The Andean adaptive allele could be a loss of function variant that increases HIF1-α in skeletal muscle.
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本文引用的文献
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rs4147929 variant minor allele increases ABCA7 gene expression and ABCA7 shows increased gene expression in Alzheimer's disease patients compared with controls.
Acta Neuropathol. 2020 May;139(5):937-940. doi: 10.1007/s00401-020-02135-9. Epub 2020 Feb 29.
2
Association of gene with high aerobic capacity of Peruvian Quechua at high altitude.
Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24006-24011. doi: 10.1073/pnas.1906171116. Epub 2019 Nov 11.
3
Rs2293871 regulates HTRA1 expression and affects cerebral small vessel stroke and Alzheimer's disease.
Brain. 2019 Nov 1;142(11):e61. doi: 10.1093/brain/awz305.
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Genetic variant rs17185536 regulates gene expression in human brain hypothalamus.
Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3347-3348. doi: 10.1073/pnas.1821550116. Epub 2019 Feb 12.
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Disease status affects the association between rs4813620 and the expression of Alzheimer's disease susceptibility gene .
Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10519-E10520. doi: 10.1073/pnas.1812975115. Epub 2018 Oct 24.
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Autoimmune disease variants regulate gene expression in human immune cells and whole blood.
Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):E7860-E7862. doi: 10.1073/pnas.1712127114. Epub 2017 Sep 7.
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The EGLN-HIF O-Sensing System: Multiple Inputs and Feedbacks.
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EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection.
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Suppression of hypoxia-inducible factor 1alpha (HIF-1alpha) transcriptional activity by the HIF prolyl hydroxylase EGLN1.
J Biol Chem. 2005 Nov 11;280(45):38102-7. doi: 10.1074/jbc.M504342200. Epub 2005 Sep 12.
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