Department of Emergency Medicine, University of Manitoba; Department of Emergency Medicine, Health Sciences Centre, Winnipeg, Manitoba, Canada.
Emerg Med Pract. 2020 Sep 15;22(Suppl 9):1-42.
While relatively uncommon, an overdose of calcium channel blockers, beta blockers, or digoxin can result in significant morbidity and mortality, and management can be complex. An acute overdose will require different management strategies than chronic toxicity while on therapeutic dosing. Toxicity from these agents must be considered in bradycardic and hypotensive patients. This supplement provides an evidence-based overview of emergency department management of calcium channel blocker overdose, beta blocker overdose, and digoxin toxicity, and focuses on the caveats of treatment for each.
虽然相对少见,但钙通道阻滞剂、β 受体阻滞剂或地高辛过量可能导致严重的发病率和死亡率,且其管理可能很复杂。急性过量与治疗剂量下的慢性中毒需要不同的管理策略。这些药物的毒性必须在心动过缓和低血压患者中考虑。本增刊提供了关于钙通道阻滞剂过量、β 受体阻滞剂过量和地高辛毒性的急诊科管理的循证概述,并重点介绍了每种药物治疗的注意事项。