European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
Nucleic Acids Res. 2021 Jan 8;49(D1):D884-D891. doi: 10.1093/nar/gkaa942.
The Ensembl project (https://www.ensembl.org) annotates genomes and disseminates genomic data for vertebrate species. We create detailed and comprehensive annotation of gene structures, regulatory elements and variants, and enable comparative genomics by inferring the evolutionary history of genes and genomes. Our integrated genomic data are made available in a variety of ways, including genome browsers, search interfaces, specialist tools such as the Ensembl Variant Effect Predictor, download files and programmatic interfaces. Here, we present recent Ensembl developments including two new website portals. Ensembl Rapid Release (http://rapid.ensembl.org) is designed to provide core tools and services for genomes as soon as possible and has been deployed to support large biodiversity sequencing projects. Our SARS-CoV-2 genome browser (https://covid-19.ensembl.org) integrates our own annotation with publicly available genomic data from numerous sources to facilitate the use of genomics in the international scientific response to the COVID-19 pandemic. We also report on other updates to our annotation resources, tools and services. All Ensembl data and software are freely available without restriction.
Ensembl 项目（https://www.ensembl.org）注释了脊椎动物物种的基因组并传播基因组数据。我们通过推断基因和基因组的进化历史，对基因结构、调控元件和变体进行详细和全面的注释，并支持比较基因组学。我们的综合基因组数据以多种方式提供，包括基因组浏览器、搜索界面、专门工具（如 Ensembl 变体效应预测器）、下载文件和编程接口。在这里，我们介绍了最近的 Ensembl 发展，包括两个新的网站门户。Ensembl 快速发布版（http://rapid.ensembl.org）旨在尽快为基因组提供核心工具和服务，并已部署用于支持大型生物多样性测序项目。我们的 SARS-CoV-2 基因组浏览器（https://covid-19.ensembl.org）将我们自己的注释与来自众多来源的公开基因组数据集成在一起，以促进在 COVID-19 大流行的国际科学应对中使用基因组学。我们还报告了我们的注释资源、工具和服务的其他更新。所有 Ensembl 数据和软件均可无限制免费获取。
